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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Ann+Fam+Med
2017 ; 15
(6
): 523-528
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Auscultation While Standing: A Basic and Reliable Method to Rule Out a Pathologic
Heart Murmur in Children
#MMPMID29133490
Lefort B
; Cheyssac E
; Soulé N
; Poinsot J
; Vaillant MC
; Nassimi A
; Chantepie A
Ann Fam Med
2017[Nov]; 15
(6
): 523-528
PMID29133490
show ga
PURPOSE: The distinction between physiologic (innocent) and pathologic (organic)
heart murmurs is not always easy in routine practice, leading too often to
unnecessary cardiology referrals and expensive investigations. We aimed to test
the hypothesis that the complete disappearance of murmur on standing can exclude
cardiac disease in children. METHODS: From January 2014 to January 2015, we
prospectively included 194 consecutive children aged 2 to 18 years who were
referred for heart murmur evaluation to pediatric cardiologists at 2 French
medical centers. Heart murmur characteristics while supine and then while
standing were recorded, and an echo-cardiogram was performed. RESULTS: Overall,
30 (15%) of the 194 children had a pathologic heart murmur as determined by an
abnormal echocardiogram. Among the 100 children (51%) who had a murmur that was
present while they were supine but completely disappeared when they stood up,
only 2 had a pathologic murmur, and just 1 of them needed further evaluation.
Complete disappearance of the heart murmur on standing therefore excluded a
pathologic murmur with a high positive predictive value of 98% and specificity of
93%, albeit with a lower sensitivity of 60%. CONCLUSIONS: Disappearance of a
heart murmur on standing is a reliable clinical tool for ruling out pathologic
heart murmurs in children aged 2 years and older. This basic clinical assessment
would avoid many unnecessary referrals to cardiologists.
|*Posture
[MESH]
|Adolescent
[MESH]
|Auscultation/*methods
[MESH]
|Child
[MESH]
|Child, Preschool
[MESH]
|Diagnosis, Differential
[MESH]
|Female
[MESH]
|Heart Murmurs/*diagnosis
[MESH]
|Humans
[MESH]
|Male
[MESH]
|Prospective Studies
[MESH]
|Referral and Consultation/statistics & numerical data
[MESH]