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10.1186/s12951-017-0311-4 http://scihub22266oqcxt.onion/10.1186/s12951-017-0311-4 C5683342!5683342!29132385     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Nanobiotechnology 2017 ; 15 (ä): ä Nephropedia Template TP {{tp|p=29132385|t=2017. Aptamer selection and applications for breast cancer diagnostics and therapy |pdf=|usr=}}{{29132385}} gab.com Text Aptamer selection and applications for breast cancer diagnostics and therapy JO: J Nanobiotechnology http://www.kidney.de/pget.php?&tw=1&pmid=29132385 #FOAvip Aptamers are short non-coding, single-stranded oligonucleotides (RNA or DNA) developed through Systematic Evolution of Ligands by Exponential enrichment (SELEX) in vitro. Similar to antibodies, aptamers can bind to specific targets with high affinity, and are considered promising therapeutic agents as they have several advantages over antibodies, including high specificity, stability, and non-immunogenicity. Furthermore, aptamers can be produced at a low cost and easily modified, and are, therefore, called ?chemical antibodies?. In the past years, a variety of aptamers specifically bound to both breast cancer biomarkers and cells had been selected. Besides, taking advantage of nanomaterials, there were a number of aptamer-nanomaterial conjugates been developed and widely investigated for diagnostics and targeted therapy of breast cancer. In this short review, we first present a systematical review of various aptamer selection methods. Then, various aptamer-based diagnostic and therapeutic strategies of breast cancer were provided. Finally, the current problems, challenges, and future perspectives in the field were thoroughly discussed. Twit Text FOAVip Aptamer selection and applications for breast cancer diagnostics and therapy ????J Nanobiotechnology http://www.kidney.de/pget.php?&tw=1&pmid=29132385 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29132385 #FOAvip English Wikipedia <ref>{{Cite pmid|29132385}}</ref> Aptamer selection and applications for breast cancer diagnostics and therapy #MMPMID29132385 Liu M; Yu X; Chen Z; Yang T; Yang D; Liu Q; Du K; Li B; Wang Z; Li S; Deng Y; He N J Nanobiotechnology 2017[]; 15 (ä): ä PMID29132385show ga Aptamers are short non-coding, single-stranded oligonucleotides (RNA or DNA) developed through Systematic Evolution of Ligands by Exponential enrichment (SELEX) in vitro. Similar to antibodies, aptamers can bind to specific targets with high affinity, and are considered promising therapeutic agents as they have several advantages over antibodies, including high specificity, stability, and non-immunogenicity. Furthermore, aptamers can be produced at a low cost and easily modified, and are, therefore, called ?chemical antibodies?. In the past years, a variety of aptamers specifically bound to both breast cancer biomarkers and cells had been selected. Besides, taking advantage of nanomaterials, there were a number of aptamer-nanomaterial conjugates been developed and widely investigated for diagnostics and targeted therapy of breast cancer. In this short review, we first present a systematical review of various aptamer selection methods. Then, various aptamer-based diagnostic and therapeutic strategies of breast cancer were provided. Finally, the current problems, challenges, and future perspectives in the field were thoroughly discussed. äAptamer selection and applications for breast cancer diagnostics and t(epmc).pdf DeepDyve Pubget Overpricing