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10.1038/s41467-017-01049-7 http://scihub22266oqcxt.onion/10.1038/s41467-017-01049-7 C5681665!5681665!29127279     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Nat+Commun 2017 ; 8 (ä): ä Nephropedia Template TP {{tp|p=29127279|t=2017. The emergence of piRNAs against transposon invasion to preserve mammalian genome integrity |pdf=|usr=}}{{29127279}} gab.com Text The emergence of piRNAs against transposon invasion to preserve mammalian genome integrity JO: Nat Commun http://www.kidney.de/pget.php?&tw=1&pmid=29127279 #FOAvip Transposable elements (TEs) contribute to the large amount of repetitive sequences in mammalian genomes and have been linked to species-specific genome innovations by rewiring regulatory circuitries. However, organisms need to restrict TE activity to ensure genome integrity, especially in germline cells to protect the transmission of genetic information to the next generation. This review features our current understandings of mammalian PIWI-interacting RNAs (piRNAs) and their role in TE regulation in spermatogenesis. Here we discuss functional implication and explore additional molecular mechanisms that inhibit transposon activity and altogether illustrate the paradoxical arms race between genome evolution and stability. Twit Text FOAVip The emergence of piRNAs against transposon invasion to preserve mammalian genome integrity ????Nat Commun http://www.kidney.de/pget.php?&tw=1&pmid=29127279 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29127279 #FOAvip English Wikipedia <ref>{{Cite pmid|29127279}}</ref> The emergence of piRNAs against transposon invasion to preserve mammalian genome integrity #MMPMID29127279 Ernst C; Odom DT; Kutter C Nat Commun 2017[]; 8 (ä): ä PMID29127279show ga Transposable elements (TEs) contribute to the large amount of repetitive sequences in mammalian genomes and have been linked to species-specific genome innovations by rewiring regulatory circuitries. However, organisms need to restrict TE activity to ensure genome integrity, especially in germline cells to protect the transmission of genetic information to the next generation. This review features our current understandings of mammalian PIWI-interacting RNAs (piRNAs) and their role in TE regulation in spermatogenesis. Here we discuss functional implication and explore additional molecular mechanisms that inhibit transposon activity and altogether illustrate the paradoxical arms race between genome evolution and stability. äThe emergence of piRNAs against transposon invasion to preserve mammal(epmc).pdf DeepDyve Pubget Overpricing