Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\28884373
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Clin+Rheumatol
2017 ; 36
(12
): 2673-2682
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Prevalence of and factors associated with renal dysfunction in rheumatoid
arthritis patients: a cross-sectional study in community hospitals
#MMPMID28884373
Mori S
; Yoshitama T
; Hirakata N
; Ueki Y
Clin Rheumatol
2017[Dec]; 36
(12
): 2673-2682
PMID28884373
show ga
This study was designed to determine the prevalence of renal dysfunction in
rheumatoid arthritis (RA) patients and to identify factors associated with this
complication. Between October 2014 and May 2015, we consecutively recruited RA
patients at rheumatology sections of community hospitals in Japan. Each patient's
absolute and body surface area (BSA)-indexed estimated glomerular filtration rate
(eGFR) values were measured twice over a 3-month interval. Renal dysfunction was
defined as absolute eGFR or BSA-indexed eGFR < 60. Albuminuria and hematuria were
also recorded. Associations between renal dysfunction and possible risk factors
were examined by multivariate logistic regression analyses. A total of 1908
outpatients with RA were included in this study. The prevalence of renal
dysfunction based on absolute eGFR and BSA-indexed eGFR was 33.8 and 18.6%,
respectively. Albuminuria was observed in 8.1% of this patient cohort, and the
prevalence of hematuria was 7.5%. Advanced age (odds ratio [OR] 7.24, p < 0.001),
female sex (OR 3.12, p < 0.001), hypertension (OR 2.22, p < 0.001), and obesity
(OR 0.59, p < 0.001) were independently associated with the risk of absolute
eGFR-based renal dysfunction. Advanced age (OR 5.19, p < 0.001) and hypertension
(OR 3.05, p < 0.001) also had associations with BSA-indexed eGFR-based renal
dysfunction. RA duration, stages, severity, and cumulative steroid dose were
considered significant risk factors in univariate analyses, but their
associations were less potent after adjustment for other covariates. Renal
dysfunction is relatively common in RA patients and is mainly associated with
advanced age and hypertension but not with RA-related factors.