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10.2967/jnumed.108.058651

http://scihub22266oqcxt.onion/10.2967/jnumed.108.058651
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C5680544!5680544!20080889
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suck abstract from ncbi


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pmid20080889      J+Nucl+Med 2010 ; 51 (2): 311-28
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  • MIRD Pamphlet No 22 (Abridged): Radiobiology and Dosimetry of ?-Particle Emitters for Targeted Radionuclide Therapy* #MMPMID20080889
  • Sgouros G; Roeske JC; McDevitt MR; Palm S; Allen BJ; Fisher DR; Brill AB; Song H; Howell RW; Akabani G
  • J Nucl Med 2010[Feb]; 51 (2): 311-28 PMID20080889show ga
  • The potential of ?-particle emitters to treat cancer has been recognized since the early 1900s. Advances in the targeted delivery of radionuclides and radionuclide conjugation chemistry, and the increased availability of ?-emitters appropriate for clinical use, have recently led to patient trials of radiopharmaceuticals labeled with ?-particle emitters. Although ?-emitters have been studied for many decades, their current use in humans for targeted therapy is an important milestone. The objective of this work is to review those aspects of the field that are pertinent to targeted ?-particle emitter therapy and to provide guidance and recommendations for human ?-particle emitter dosimetry.
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