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10.1084/jem.20171000

http://scihub22266oqcxt.onion/10.1084/jem.20171000
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C5679166!5679166!28830910
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suck abstract from ncbi


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pmid28830910      J+Exp+Med 2017 ; 214 (11): 3183-95
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  • Redefining thymus medulla specialization for central tolerance #MMPMID28830910
  • Cosway EJ; Lucas B; James KD; Parnell SM; Carvalho-Gaspar M; White AJ; Tumanov AV; Jenkinson WE; Anderson G
  • J Exp Med 2017[Nov]; 214 (11): 3183-95 PMID28830910show ga
  • The thymus medulla prevents T cell?driven autoimmunity via central tolerance. Cosway et al. show that this specialization occurs independently of the topology that classically defines its structure and demonstrate that medulla function requires LT?R-mediated regulation of dendritic cells for negative selection.
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