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10.3748/wjg.v23.i40.7343

http://scihub22266oqcxt.onion/10.3748/wjg.v23.i40.7343
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suck abstract from ncbi


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pmid29142482      World+J+Gastroenterol 2017 ; 23 (40): 7343-6
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  • S-Adenosyl-L-methionine towards hepatitis C virus expression: Need to consider S-Adenosyl-L-methionine?s chemistry, physiology and pharmacokinetics #MMPMID29142482
  • Tsikas D; Hanff E; Bollenbach A
  • World J Gastroenterol 2017[Oct]; 23 (40): 7343-6 PMID29142482show ga
  • S-Adenosyl-L-methionine (SAM) is a cofactor serving as a methyl donor in numerous enzymatic reactions. It has been reported that SAM has the potential to modify antioxidant-enzymes, glutathione-biosynthesis and methionine adenosyltransferases-1/2 in hepatitis C virus -expressing cells at millimolar concentrations. The efficacy of SAM at micromolar concentrations and the underlying mechanisms remain to be demonstrated.
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