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10.4155/fsoa-2017-0010 http://scihub22266oqcxt.onion/10.4155/fsoa-2017-0010 C5674217!5674217!29134113     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Future+Sci+OA 2017 ; 3 (4): ä Nephropedia Template TP {{tp|p=29134113|t=2017. Research advances in kinase enzymes and inhibitors for cardiovascular disease treatment |pdf=|usr=}}{{29134113}} gab.com Text Research advances in kinase enzymes and inhibitors for cardiovascular disease treatment JO: Future Sci OA http://www.kidney.de/pget.php?&tw=1&pmid=29134113 #FOAvip The targeting of protein kinases has great future potential for the design of new drugs against cardiovascular diseases (CVDs). Enormous efforts have been made toward achieving this aim. Unfortunately, kinase inhibitors designed to treat CVDs have suffered from numerous limitations such as poor selectivity, bad permeability and toxicity. So, where are we now in terms of discovering effective kinase targeting drugs to treat CVDs? Various drug design techniques have been approached for this purpose since the discovery of the inhibitory activity of Staurosporine against protein kinase C in 1986. This review aims to provide context for the status of several emerging classes of direct kinase modulators to treat CVDs and discuss challenges that are preventing scientists from finding new kinase drugs to treat heart disease. Twit Text FOAVip Research advances in kinase enzymes and inhibitors for cardiovascular disease treatment ????Future Sci OA http://www.kidney.de/pget.php?&tw=1&pmid=29134113 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29134113 #FOAvip English Wikipedia <ref>{{Cite pmid|29134113}}</ref> Research advances in kinase enzymes and inhibitors for cardiovascular disease treatment #MMPMID29134113 Shahin R; Shaheen O; El-Dahiyat F; Habash M; Saffour S Future Sci OA 2017[Nov]; 3 (4): ä PMID29134113show ga The targeting of protein kinases has great future potential for the design of new drugs against cardiovascular diseases (CVDs). Enormous efforts have been made toward achieving this aim. Unfortunately, kinase inhibitors designed to treat CVDs have suffered from numerous limitations such as poor selectivity, bad permeability and toxicity. So, where are we now in terms of discovering effective kinase targeting drugs to treat CVDs? Various drug design techniques have been approached for this purpose since the discovery of the inhibitory activity of Staurosporine against protein kinase C in 1986. This review aims to provide context for the status of several emerging classes of direct kinase modulators to treat CVDs and discuss challenges that are preventing scientists from finding new kinase drugs to treat heart disease. äResearch advances in kinase enzymes and inhibitors for cardiovascular (epmc).pdf DeepDyve Pubget Overpricing