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10.1097/MD.0000000000008402

http://scihub22266oqcxt.onion/10.1097/MD.0000000000008402
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C5671870!5671870 !29069037
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suck abstract from ncbi


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pmid29069037
      Medicine+(Baltimore) 2017 ; 96 (43 ): e8402
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  • Dopamine versus norepinephrine in the treatment of cardiogenic shock: A PRISMA-compliant meta-analysis #MMPMID29069037
  • Rui Q ; Jiang Y ; Chen M ; Zhang N ; Yang H ; Zhou Y
  • Medicine (Baltimore) 2017[Oct]; 96 (43 ): e8402 PMID29069037 show ga
  • BACKGROUND: Guidelines recommend that norepinephrine (NA) should be used to reach the target mean arterial pressure (MAP) during cardiogenic shock (CS), rather than epinephrine and dopamine (DA). However, there has actually been few studies on comparing norepinephrine with dopamine and their results conflicts. These studies raise a heat discussion. This study aimed to validate the effectiveness of norepinephrine for treating CS in comparison with dopamine. METHODS: We performed a meta-analysis of randomized controlled trials (RCTs) to assess pooled estimates of risk ratio (RR) and 95% confidence interval (CI) for 28-day mortality, incidence of arrhythmic events, gastrointestinal reaction, and some indexes after treatment. RESULTS: Compared with dopamine, patients receiving norepinephrine had a lower 28-day mortality (RR 1.611 [95% CI 1.219-2.129]; P?
  • |Cardiotonic Agents/*therapeutic use [MESH]
  • |Dopamine/*therapeutic use [MESH]
  • |Humans [MESH]
  • |Norepinephrine/*therapeutic use [MESH]
  • |Odds Ratio [MESH]
  • |Randomized Controlled Trials as Topic [MESH]
  • |Shock, Cardiogenic/*drug therapy/etiology/mortality [MESH]


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