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10.18632/oncotarget.18789 http://scihub22266oqcxt.onion/10.18632/oncotarget.18789 C5669947!5669947!29137321     free     free     free Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 235.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Oncotarget 2017 ; 8 (47): 83030-7 Nephropedia Template TP {{tp|p=29137321|t=2017. The role of indoxyl sulfate in renal anemia in patients with chronic kidney disease |pdf=|usr=}}{{29137321}} gab.com Text The role of indoxyl sulfate in renal anemia in patients with chronic kidney disease JO: Oncotarget http://www.kidney.de/pget.php?&tw=1&pmid=29137321 #FOAvip Renal anemia is a common complication in patients with advanced chronic kidney disease. In vitro studies have shown that indoxyl sulfate decreases erythropoietin production. Whether this effect is seen in vivo remains unclear. Our goal was to explore the role of indoxyl sulfate in renal anemia. We found serum indoxyl sulfate levels are significantly and negatively associated with erythropoietin levels in human. A multiple stepwise linear regression analyses after adjustment for other independent parameters revealed that free indoxyl sulfate, and total indoxyl sulfate were significantly associated with erythropoietin levels. In animal studies, erythropoietin gene and protein expression were markedly inhibited in rats with chronic kidney disease; however, this effect was significantly reversed by lowering serum indoxyl sulfate with AST-120. Indoxyl sulfate may also inhibit erythropoietin expression in animal models with chronic kidney disease. These findings further support the role of indoxyl sulfate in the development of renal anemia. Twit Text FOAVip The role of indoxyl sulfate in renal anemia in patients with chronic kidney disease ????Oncotarget http://www.kidney.de/pget.php?&tw=1&pmid=29137321 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29137321 #FOAvip English Wikipedia <ref>{{Cite pmid|29137321}}</ref> The role of indoxyl sulfate in renal anemia in patients with chronic kidney disease #MMPMID29137321 Wu CJ; Chen CY; Lai TS; Wu PC; Chuang CK; Sun FJ; Liu HL; Chen HH; Yeh HI; Lin CS; Lin CJ Oncotarget 2017[Oct]; 8 (47): 83030-7 PMID29137321show ga Renal anemia is a common complication in patients with advanced chronic kidney disease. In vitro studies have shown that indoxyl sulfate decreases erythropoietin production. Whether this effect is seen in vivo remains unclear. Our goal was to explore the role of indoxyl sulfate in renal anemia. We found serum indoxyl sulfate levels are significantly and negatively associated with erythropoietin levels in human. A multiple stepwise linear regression analyses after adjustment for other independent parameters revealed that free indoxyl sulfate, and total indoxyl sulfate were significantly associated with erythropoietin levels. In animal studies, erythropoietin gene and protein expression were markedly inhibited in rats with chronic kidney disease; however, this effect was significantly reversed by lowering serum indoxyl sulfate with AST-120. Indoxyl sulfate may also inhibit erythropoietin expression in animal models with chronic kidney disease. These findings further support the role of indoxyl sulfate in the development of renal anemia. äThe role of indoxyl sulfate in renal anemia in patients with chronic k(epmc).pdf DeepDyve Pubget Overpricing