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10.5009/gnl16365

http://scihub22266oqcxt.onion/10.5009/gnl16365
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C5669592!5669592!28292174
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suck abstract from ncbi


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pmid28292174      Gut+Liver 2017 ; 11 (6): 771-80
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  • Extrahepatic Manifestations of Primary Biliary Cholangitis #MMPMID28292174
  • Chalifoux SL; Konyn PG; Choi G; Saab S
  • Gut Liver 2017[Nov]; 11 (6): 771-80 PMID28292174show ga
  • Primary biliary cholangitis (PBC) is an autoimmune liver disease characterized by progressive destruction of the intrahepatic bile ducts, leading to cholestasis. PBC is known to have both hepatic and extrahepatic manifestations. Extrahepatic manifestations are seen in up to 73% of patients with PBC, with the most common being Sjogren?s syndrome, thyroid dysfunction and systemic sclerosis. It is thought that patients with PBC are at increased risk of developing these extrahepatic manifestations, almost all of which are autoimmune, because patients with autoimmune disease are at higher risk of developing another autoimmune condition. Due to the high prevalence of extrahepatic diseases in patients with PBC, it is important to complete a thorough medical history at the time of diagnosis. Prompt recognition of extrahepatic disease can lead to improved patient outcomes and quality of life. The following review summarizes the most common extrahepatic conditions associated with PBC.
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