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10.5009/gnl16523

http://scihub22266oqcxt.onion/10.5009/gnl16523
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C5669590!5669590!28494577
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suck abstract from ncbi


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pmid28494577      Gut+Liver 2017 ; 11 (6): 747-60
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  • Sessile Serrated Adenomas: How to Detect, Characterize and Resect #MMPMID28494577
  • Ma MX; Bourke MJ
  • Gut Liver 2017[Nov]; 11 (6): 747-60 PMID28494577show ga
  • Serrated polyps are important contributors to the burden of colorectal cancers (CRC). These lesions were once considered to have no malignant potential, but currently up to 30% of all CRC are recognized to arise from the serrated neoplasia pathway. The primary premalignant lesions are sessile serrated adenomas/polyps (SSA/Ps), although traditional serrated adenomas are relatively uncommon. Compared to conventional adenomas, SSA/Ps are morphologically subtle with indistinct borders, may be difficult to detect endoscopically, are more prevalent than previously thought, are associated with synchronous and metachronous advanced neoplasia, and have a higher risk of incomplete resection. Although many lesions remain ?dormant,? progressive disease is associated with the development of dysplasia and more rapid progression to CRC. As a result, SSA/Ps are strongly implicated in the development of interval cancers. These factors represent unique challenges that require a meticulous approach to their management. In this review, we summarize the contemporary literature on the characterization, detection and resection of SSA/Ps.
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