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2017 ; 4
(1
): 123-126
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
A case of type 2 diabetes mellitus with metformin-associated lactic acidosis
initially presenting the appearance of a sulfonylurea-related hypoglycemic
attack
#MMPMID29123848
Nishihama K
; Maki K
; Okano Y
; Hashimoto R
; Hotta Y
; Uemura M
; Yasuma T
; Suzuki T
; Hayashi T
; Ishikawa E
; Yano Y
; Gabazza EC
; Ito M
; Takei Y
Acute Med Surg
2017[Jan]; 4
(1
): 123-126
PMID29123848
show ga
CASE: A 64-year-old Japanese woman with diabetes mellitus was admitted for
hypoglycemia. Her diabetes had been under good control with glimepiride,
voglibose, exenatide, and metformin for a few years. Although overt proteinuria
was observed, the serum creatinine values were within normal range during the
routine outpatient follow-up. Hypoglycemic attack caused by glimepiride and loss
of appetite by urinary tract infection were diagnosed. Then, metformin-associated
lactic acidosis with acute renal failure caused by dehydration was detected.
OUTCOME: Her condition was improved by continuous veno-venous hemodiafiltration
and hemodialysis, known to be useful to remove metformin. CONCLUSION: We reported
a case of metformin-associated lactic acidosis with hypoglycemia during routine
treatment of diabetes that was successfully rescued by early renal replacement
therapy.