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10.1186/s13059-017-1341-9

http://scihub22266oqcxt.onion/10.1186/s13059-017-1341-9
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suck abstract from ncbi


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pmid29089032
      Genome+Biol 2017 ; 18 (1 ): 210
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  • New reference genome sequences of hot pepper reveal the massive evolution of plant disease-resistance genes by retroduplication #MMPMID29089032
  • Kim S ; Park J ; Yeom SI ; Kim YM ; Seo E ; Kim KT ; Kim MS ; Lee JM ; Cheong K ; Shin HS ; Kim SB ; Han K ; Lee J ; Park M ; Lee HA ; Lee HY ; Lee Y ; Oh S ; Lee JH ; Choi E ; Choi E ; Lee SE ; Jeon J ; Kim H ; Choi G ; Song H ; Lee J ; Lee SC ; Kwon JK ; Lee HY ; Koo N ; Hong Y ; Kim RW ; Kang WH ; Huh JH ; Kang BC ; Yang TJ ; Lee YH ; Bennetzen JL ; Choi D
  • Genome Biol 2017[Nov]; 18 (1 ): 210 PMID29089032 show ga
  • BACKGROUND: Transposable elements are major evolutionary forces which can cause new genome structure and species diversification. The role of transposable elements in the expansion of nucleotide-binding and leucine-rich-repeat proteins (NLRs), the major disease-resistance gene families, has been unexplored in plants. RESULTS: We report two high-quality de novo genomes (Capsicum baccatum and C. chinense) and an improved reference genome (C. annuum) for peppers. Dynamic genome rearrangements involving translocations among chromosomes 3, 5, and 9 were detected in comparison between C. baccatum and the two other peppers. The amplification of athila LTR-retrotransposons, members of the gypsy superfamily, led to genome expansion in C. baccatum. In-depth genome-wide comparison of genes and repeats unveiled that the copy numbers of NLRs were greatly increased by LTR-retrotransposon-mediated retroduplication. Moreover, retroduplicated NLRs are abundant across the angiosperms and, in most cases, are lineage-specific. CONCLUSIONS: Our study reveals that retroduplication has played key roles for the massive emergence of NLR genes including functional disease-resistance genes in pepper plants.
  • |*Evolution, Molecular [MESH]
  • |*Gene Duplication [MESH]
  • |*Genes, Plant [MESH]
  • |Capsicum/*genetics [MESH]
  • |Chromosomes, Plant/genetics [MESH]
  • |Disease Resistance/*genetics [MESH]
  • |Genetic Speciation [MESH]
  • |Molecular Sequence Annotation [MESH]
  • |Multigene Family [MESH]
  • |NLR Proteins/genetics [MESH]
  • |Open Reading Frames/genetics [MESH]
  • |Phylogeny [MESH]
  • |Plant Diseases/*genetics/*immunology [MESH]
  • |Reference Standards [MESH]
  • |Retroelements/*genetics [MESH]
  • |Sequence Analysis, RNA [MESH]
  • |Species Specificity [MESH]


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