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2017 ; 18
(1
): 210
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New reference genome sequences of hot pepper reveal the massive evolution of
plant disease-resistance genes by retroduplication
#MMPMID29089032
Kim S
; Park J
; Yeom SI
; Kim YM
; Seo E
; Kim KT
; Kim MS
; Lee JM
; Cheong K
; Shin HS
; Kim SB
; Han K
; Lee J
; Park M
; Lee HA
; Lee HY
; Lee Y
; Oh S
; Lee JH
; Choi E
; Choi E
; Lee SE
; Jeon J
; Kim H
; Choi G
; Song H
; Lee J
; Lee SC
; Kwon JK
; Lee HY
; Koo N
; Hong Y
; Kim RW
; Kang WH
; Huh JH
; Kang BC
; Yang TJ
; Lee YH
; Bennetzen JL
; Choi D
Genome Biol
2017[Nov]; 18
(1
): 210
PMID29089032
show ga
BACKGROUND: Transposable elements are major evolutionary forces which can cause
new genome structure and species diversification. The role of transposable
elements in the expansion of nucleotide-binding and leucine-rich-repeat proteins
(NLRs), the major disease-resistance gene families, has been unexplored in
plants. RESULTS: We report two high-quality de novo genomes (Capsicum baccatum
and C. chinense) and an improved reference genome (C. annuum) for peppers.
Dynamic genome rearrangements involving translocations among chromosomes 3, 5,
and 9 were detected in comparison between C. baccatum and the two other peppers.
The amplification of athila LTR-retrotransposons, members of the gypsy
superfamily, led to genome expansion in C. baccatum. In-depth genome-wide
comparison of genes and repeats unveiled that the copy numbers of NLRs were
greatly increased by LTR-retrotransposon-mediated retroduplication. Moreover,
retroduplicated NLRs are abundant across the angiosperms and, in most cases, are
lineage-specific. CONCLUSIONS: Our study reveals that retroduplication has played
key roles for the massive emergence of NLR genes including functional
disease-resistance genes in pepper plants.