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10.1097/MD.0000000000008229

http://scihub22266oqcxt.onion/10.1097/MD.0000000000008229
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C5662375!5662375!29049209
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suck abstract from ncbi


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pmid29049209      Medicine+(Baltimore) 2017 ; 96 (42): ä
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  • Pravastatin for prevention of HELLP syndrome: A case report #MMPMID29049209
  • Otten LA; van der Ven K; Kühr M; Gembruch U; Merz WM
  • Medicine (Baltimore) 2017[Oct]; 96 (42): ä PMID29049209show ga
  • Rationale:: Pravastatin has emerged for prevention and treatment of preeclampsia; no reports are available on pravastatin and HELLP (hemolysis, elevated liver enzymes and low platelets) syndrome. Patient concerns:: The first pregnancy necessitated termination of pregnancy at gestational age (GA) 20+5 for HELLP. Intrauterine fetal death at GA 22+5 occurred in the second pregnancy, whilst on temporizing management of HELLP. Diagnoses:: Severe, recurrent early-onset HELLP syndrome. Interventions:: In her fourth pregnancy, pravastatin was commenced at GA 13. Outcomes:: The course of pregnancy was uncomplicated, and a healthy, appropriate for gestational age fetus was delivered at term. Lessons:: Pravastatin may be effective in prevention of HELLP. The hepatic uptake may be of particular advantage.
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