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10.1186/s12915-017-0434-y

http://scihub22266oqcxt.onion/10.1186/s12915-017-0434-y
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C5662103!5662103!29084517
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suck abstract from ncbi

pmid29084517      BMC+Biol 2017 ; 15 (ä): ä
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  • Detecting positive selection in the genome #MMPMID29084517
  • Booker TR; Jackson BC; Keightley PD
  • BMC Biol 2017[]; 15 (ä): ä PMID29084517show ga
  • Population geneticists have long sought to understand the contribution of natural selection to molecular evolution. A variety of approaches have been proposed that use population genetics theory to quantify the rate and strength of positive selection acting in a species? genome. In this review we discuss methods that use patterns of between-species nucleotide divergence and within-species diversity to estimate positive selection parameters from population genomic data. We also discuss recently proposed methods to detect positive selection from a population?s haplotype structure. The application of these tests has resulted in the detection of pervasive adaptive molecular evolution in multiple species.
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