Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=29113267
&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215
Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\29113267
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Oncol+Lett
2017 ; 14
(5
): 6198-6202
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Overexpression of Rictor protein in colorectal cancer is correlated with tumor
progression and prognosis
#MMPMID29113267
Wang L
; Qi J
; Yu J
; Chen H
; Zou Z
; Lin X
; Guo L
Oncol Lett
2017[Nov]; 14
(5
): 6198-6202
PMID29113267
show ga
In order to understand the clinical significance of rapamycin-insensitive
companion of mammalian target of rapamycin (Rictor) in colorectal cancer (CRC),
62 CRC tissue samples excised during operations were evaluated by
immunohistochemistry. Analysis of the association between the expression level of
Rictor protein and clinicopathological parameters demonstrated that the
expression level of Rictor in CRC tissues was significantly higher than that in
paracarcinoma tissues (P<0.0001). In cellular experiments, this result was
further confirmed by comparing differences in Rictor expression between the CRC
cell lines HCT116, SW480 and LoVo, and the human normal liver cell line HL-7702.
It was also noticed that the expression of Rictor was associated with Dukes
stage, lymphatic metastasis and prognosis, as determined by ?(2) test,
Kaplan-Meier analysis and log-rank test. These results suggest that Rictor may be
a novel target for the treatment and prognostic assessment of CRC patients in the
future.