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10.1371/journal.pone.0186971 http://scihub22266oqcxt.onion/10.1371/journal.pone.0186971 C5658108!5658108!29073213     free     free     free Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       PLoS+One 2017 ; 12 (10): ä Nephropedia Template TP {{tp|p=29073213|t=2017. Cytokine-induced killer cells: A novel treatment for allergic airway inflammation |pdf=|usr=}}{{29073213}} gab.com Text Cytokine-induced killer cells: A novel treatment for allergic airway inflammation JO: PLoS One http://www.kidney.de/pget.php?&tw=1&pmid=29073213 #FOAvip The effectiveness of cytokine-induced killer (CIK) cells for treatment of cancers has long been appreciated. Here, we report for the first time that CIK cells can be applied to treat allergic airway inflammation. Adopting from an established protocol with some modifications, we generated CIK cells ex vivo from mouse T cells, and examined their effectiveness in treatment of allergic airway inflammation using the ovalbumin-induced model of allergic airway inflammation. Based upon evaluation of bronchoalveolar lavage cellularity, T helper type2 cytokine levels and lung histology, all of which are important parameters for determining the severity of allergic airway inflammation, diseased mice treated with CIK cells showed significant reductions in all the parameters without any obvious adverse effects. Interestingly, the observed effects were comparable to those treated with dexamethasone. Thus, our study provides a novel application of CIK cells in treatment of allergic airway inflammation. Twit Text FOAVip Cytokine-induced killer cells: A novel treatment for allergic airway inflammation ????PLoS One http://www.kidney.de/pget.php?&tw=1&pmid=29073213 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29073213 #FOAvip English Wikipedia <ref>{{Cite pmid|29073213}}</ref> Cytokine-induced killer cells: A novel treatment for allergic airway inflammation #MMPMID29073213 Pluangnooch P; Timalsena S; Wongkajornsilp A; Soontrapa K PLoS One 2017[]; 12 (10): ä PMID29073213show ga The effectiveness of cytokine-induced killer (CIK) cells for treatment of cancers has long been appreciated. Here, we report for the first time that CIK cells can be applied to treat allergic airway inflammation. Adopting from an established protocol with some modifications, we generated CIK cells ex vivo from mouse T cells, and examined their effectiveness in treatment of allergic airway inflammation using the ovalbumin-induced model of allergic airway inflammation. Based upon evaluation of bronchoalveolar lavage cellularity, T helper type2 cytokine levels and lung histology, all of which are important parameters for determining the severity of allergic airway inflammation, diseased mice treated with CIK cells showed significant reductions in all the parameters without any obvious adverse effects. Interestingly, the observed effects were comparable to those treated with dexamethasone. Thus, our study provides a novel application of CIK cells in treatment of allergic airway inflammation. äCytokine-induced killer cells: A novel treatment for allergic airway i(epmc).pdf DeepDyve Pubget Overpricing