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10.18632/oncotarget.20901 http://scihub22266oqcxt.onion/10.18632/oncotarget.20901 C5655254!5655254!29113359     free     free     free Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Oncotarget 2017 ; 8 (46): 80971-80 Nephropedia Template TP {{tp|p=29113359|t=2017. Hepatointestinal complications in polycystic kidney disease |pdf=|usr=}}{{29113359}} gab.com Text Hepatointestinal complications in polycystic kidney disease JO: Oncotarget http://www.kidney.de/pget.php?&tw=1&pmid=29113359 #FOAvip Background: The objective of this study was to determine the incidence of major hepatointestinal complications in patients with polycystic kidney disease (PKD). Methods: We analyzed the Taiwan National Health Insurance claims data (2000?2010) of 6031 patients with PKD and 23,976 non-PKD hospitalized controls. The control cohort was propensity score matched with the PKD cohort at a 1:4 ratio. All patients were followed up from the index date to the first inpatient diagnosis of hepatointestinal complications, death, or 31 December, 2011. Cox proportional hazard regression models were used to identify the risk of outcome after adjustment for potential confounders. Results: The incidence rates of acute pancreatitis, cholangitis, peptic ulcer bleeding, and cirrhosis were 5.72, 4.01, 19.9, and 5.46 per 1000 person-years, respectively, in the PKD cohort. Compared with the non-PKD controls, patients with PKD exhibited an increased risk of hospitalization for acute pancreatitis, cholangitis, peptic ulcer bleeding, and cirrhosis (adjusted subhazard ratio [aSHR]: 2.36, 95% confidence interval [95% CI], 1.95?2.84]; 2.36, [95% CI, 1.95?2.84]; 2.41, [95% CI, 1.93?3.01]; 2.41, [95% CI, 2.17?2.67]; and 1.39, [95% CI, 1.16?1.66], respectively; all p < 0.001). PKD, chronic kidney disease, and alcoholism were independent predictors of all these hepatointestinal complications. Kaplan?Meier analysis revealed an increased overall mortality in patients with PKD who developed acute pancreatitis and peptic ulcer bleeding (log-rank p < 0.05). Conclusion: PKD is associated with clinically significant extrarenal complications including acute pancreatitis, cholangitis, peptic ulcer bleeding, and cirrhosis. Twit Text FOAVip Hepatointestinal complications in polycystic kidney disease ????Oncotarget http://www.kidney.de/pget.php?&tw=1&pmid=29113359 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29113359 #FOAvip English Wikipedia <ref>{{Cite pmid|29113359}}</ref> Hepatointestinal complications in polycystic kidney disease #MMPMID29113359 Huang ST; Chuang YW; Yu TM; Lin CL; Jeng LB Oncotarget 2017[Oct]; 8 (46): 80971-80 PMID29113359show ga Background: The objective of this study was to determine the incidence of major hepatointestinal complications in patients with polycystic kidney disease (PKD). Methods: We analyzed the Taiwan National Health Insurance claims data (2000?2010) of 6031 patients with PKD and 23,976 non-PKD hospitalized controls. The control cohort was propensity score matched with the PKD cohort at a 1:4 ratio. All patients were followed up from the index date to the first inpatient diagnosis of hepatointestinal complications, death, or 31 December, 2011. Cox proportional hazard regression models were used to identify the risk of outcome after adjustment for potential confounders. Results: The incidence rates of acute pancreatitis, cholangitis, peptic ulcer bleeding, and cirrhosis were 5.72, 4.01, 19.9, and 5.46 per 1000 person-years, respectively, in the PKD cohort. Compared with the non-PKD controls, patients with PKD exhibited an increased risk of hospitalization for acute pancreatitis, cholangitis, peptic ulcer bleeding, and cirrhosis (adjusted subhazard ratio [aSHR]: 2.36, 95% confidence interval [95% CI], 1.95?2.84]; 2.36, [95% CI, 1.95?2.84]; 2.41, [95% CI, 1.93?3.01]; 2.41, [95% CI, 2.17?2.67]; and 1.39, [95% CI, 1.16?1.66], respectively; all p < 0.001). PKD, chronic kidney disease, and alcoholism were independent predictors of all these hepatointestinal complications. Kaplan?Meier analysis revealed an increased overall mortality in patients with PKD who developed acute pancreatitis and peptic ulcer bleeding (log-rank p < 0.05). Conclusion: PKD is associated with clinically significant extrarenal complications including acute pancreatitis, cholangitis, peptic ulcer bleeding, and cirrhosis. äHepatointestinal complications in polycystic kidney disease (epmc).pdf DeepDyve Pubget Overpricing