Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.2174/1570159X15666170113122120 http://scihub22266oqcxt.onion/10.2174/1570159X15666170113122120 C5652015!5652015!28088912     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Curr+Neuropharmacol 2017 ; 15 (7): 951-62 Nephropedia Template TP {{tp|p=28088912|t=2017. Melatonin as a Therapeutic Resource for Inflammatory Visual Diseases |pdf=|usr=}}{{28088912}} gab.com Text Melatonin as a Therapeutic Resource for Inflammatory Visual Diseases JO: Curr Neuropharmacol http://www.kidney.de/pget.php?&tw=1&pmid=28088912 #FOAvip Background: : Uveitis and optic neuritis are prevalent ocular inflammatory diseases, and highly damaging ocular conditions. Both diseases are currently treated with corticosteroids, but they do not have adequate efficacy and are often associated with severe side effects. Thus, uveitis and optic neuritis remain a challenging field to ophthalmologists and a significant public health concern. Objective: : This review summarizes findings showing the benefits of a treatment with melatonin in experimental models of these inflammatory ocular diseases. Results: : Oxidative and nitrosative damage, tumor necrosis factor, and prostaglandin production have been involved in the pathogeny of uveitis and optic neuritis. Melatonin is an efficient antioxidant and antinitridergic, and has the ability to reduce prostaglandin and tumor necrosis factor levels both in the retina and optic nerve. Moreover, melatonin not only prevents functional and structural consequences of experimental uveitis and optic neuritis, but it is also capable of suppressing the actively ongoing ocular inflammatory response. Conclusions:: Since melatonin protects ocular tissues against inflammation, it could be a potentially useful anti-inflammatory therapy in ophthalmology. Twit Text FOAVip Melatonin as a Therapeutic Resource for Inflammatory Visual Diseases ????Curr Neuropharmacol http://www.kidney.de/pget.php?&tw=1&pmid=28088912 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28088912 #FOAvip English Wikipedia <ref>{{Cite pmid|28088912}}</ref> Melatonin as a Therapeutic Resource for Inflammatory Visual Diseases #MMPMID28088912 Aranda ML; Fleitas MFG; Dieguez H; Iaquinandi A; Sande PH; Dorfman D; Rosenstein RE Curr Neuropharmacol 2017[Oct]; 15 (7): 951-62 PMID28088912show ga Background: : Uveitis and optic neuritis are prevalent ocular inflammatory diseases, and highly damaging ocular conditions. Both diseases are currently treated with corticosteroids, but they do not have adequate efficacy and are often associated with severe side effects. Thus, uveitis and optic neuritis remain a challenging field to ophthalmologists and a significant public health concern. Objective: : This review summarizes findings showing the benefits of a treatment with melatonin in experimental models of these inflammatory ocular diseases. Results: : Oxidative and nitrosative damage, tumor necrosis factor, and prostaglandin production have been involved in the pathogeny of uveitis and optic neuritis. Melatonin is an efficient antioxidant and antinitridergic, and has the ability to reduce prostaglandin and tumor necrosis factor levels both in the retina and optic nerve. Moreover, melatonin not only prevents functional and structural consequences of experimental uveitis and optic neuritis, but it is also capable of suppressing the actively ongoing ocular inflammatory response. Conclusions:: Since melatonin protects ocular tissues against inflammation, it could be a potentially useful anti-inflammatory therapy in ophthalmology. äMelatonin as a Therapeutic Resource for Inflammatory Visual Diseases (epmc).pdf DeepDyve Pubget Overpricing