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10.1155/2017/1606854 http://scihub22266oqcxt.onion/10.1155/2017/1606854 C5646338!5646338!29109865     free     free     free Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Ophthalmol 2017 ; 2017 (ä): ä Nephropedia Template TP {{tp|p=29109865|t=2017. OM-101 Decreases the Fibrotic Response Associated with Proliferative Vitreoretinopathy |pdf=|usr=}}{{29109865}} gab.com Text OM-101 Decreases the Fibrotic Response Associated with Proliferative Vitreoretinopathy JO: J Ophthalmol http://www.kidney.de/pget.php?&tw=1&pmid=29109865 #FOAvip Purpose: This study aimed to investigate the effect of OM-101 on the fibrotic response occurring in proliferative vitreoretinopathy (PVR) in an animal model. Methods: Antifibrotic effect of OM-101 was investigated in vivo. As control, eight weeks old c57black mice underwent intravitreal injection with Hepes (group A) or dispase (0.3?units), to induce retinal detachment (RD) and PVR. The dispase-injected mice were randomly divided into two groups B and C (N = 25 mice); in group C, the eyes were treated with intravitreal injection of OM-101 (3??l), and group B with PBS, as a control. After additional five days, mice were injected with the same initial treatment. Three days later, mice were euthanized, and the eyes were enucleated and processed for histological analysis. Results: Intravitreal injection of dispase caused RD in 64% of the mice in group B, and 93% of those mice had PVR. Only 32% of mice treated with OM-101 and dispase (group C) developed RD, and only 25% of those developed PVR. Conclusions: OM-101 was found effective in reducing the incidence of RD and PVR maintaining the normal architecture of the retina. This study suggests that OM-101 is a potentially effective and safe drug for the treatment of PVR patients. Twit Text FOAVip OM-101 Decreases the Fibrotic Response Associated with Proliferative Vitreoretinopathy ????J Ophthalmol http://www.kidney.de/pget.php?&tw=1&pmid=29109865 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=29109865 #FOAvip English Wikipedia <ref>{{Cite pmid|29109865}}</ref> OM-101 Decreases the Fibrotic Response Associated with Proliferative Vitreoretinopathy #MMPMID29109865 Dvashi Z; Ben-Yaakov K; Weinberg T; Greenwald Y; Pollack A J Ophthalmol 2017[]; 2017 (ä): ä PMID29109865show ga Purpose: This study aimed to investigate the effect of OM-101 on the fibrotic response occurring in proliferative vitreoretinopathy (PVR) in an animal model. Methods: Antifibrotic effect of OM-101 was investigated in vivo. As control, eight weeks old c57black mice underwent intravitreal injection with Hepes (group A) or dispase (0.3?units), to induce retinal detachment (RD) and PVR. The dispase-injected mice were randomly divided into two groups B and C (N = 25 mice); in group C, the eyes were treated with intravitreal injection of OM-101 (3??l), and group B with PBS, as a control. After additional five days, mice were injected with the same initial treatment. Three days later, mice were euthanized, and the eyes were enucleated and processed for histological analysis. Results: Intravitreal injection of dispase caused RD in 64% of the mice in group B, and 93% of those mice had PVR. Only 32% of mice treated with OM-101 and dispase (group C) developed RD, and only 25% of those developed PVR. Conclusions: OM-101 was found effective in reducing the incidence of RD and PVR maintaining the normal architecture of the retina. This study suggests that OM-101 is a potentially effective and safe drug for the treatment of PVR patients. äOM-101 Decreases the Fibrotic Response Associated with Proliferative V(epmc).pdf DeepDyve Pubget Overpricing