Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1038/mi.2017.32 http://scihub22266oqcxt.onion/10.1038/mi.2017.32 C5638662!5638662 !28401938     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\28401938 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Mucosal+Immunol 2018 ; 11 (1 ): 199-208 Nephropedia Template TP {{tp|p=28401938 |t=2018. Novel protective mechanism for interleukin-33 at the mucosal barrier during influenza-associated bacterial superinfection |pdf=|usr=}}{{28401938 }} gab.com Text Novel protective mechanism for interleukin-33 at the mucosal barrier during influenza-associated bacterial superinfection JO: Mucosal Immunol http://www.kidney.de/pget.php?&tw=1&pmid=28401938 #FOAvip Influenza A is a highly contagious respiratory virus that causes seasonal epidemics and occasional worldwide pandemics. The primary cause of influenza-related mortality is bacterial superinfection. There are numerous mechanisms by which preceding influenza infection attenuates host defense, allowing for increased susceptibility to bacterial pneumonia. Herein, we demonstrate that influenza inhibits Staphylococcus aureus-induced production of interleukin-33 (IL-33). Restoration of IL-33 during influenza A and methicillin-resistant S. aureus superinfection enhanced bacterial clearance and improved mortality. Innate lymphoid Type 2 cells and alternatively activated macrophages are not required for IL-33-mediated protection during superinfection. We show that IL-33 treatment resulted in neutrophil recruitment to the lung, associated with improved bacterial clearance. These findings identify a novel role for IL-33 in antibacterial host defense at the mucosal barrier. Twit Text FOAVip Novel protective mechanism for interleukin-33 at the mucosal barrier during influenza-associated bacterial superinfection ????Mucosal Immunol http://www.kidney.de/pget.php?&tw=1&pmid=28401938 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28401938 #FOAvip English Wikipedia <ref>{{Cite pmid|28401938 }}</ref> Novel protective mechanism for interleukin-33 at the mucosal barrier during influenza-associated bacterial superinfection #MMPMID28401938 Robinson KM ; Ramanan K ; Clay ME ; McHugh KJ ; Rich HE ; Alcorn JF Mucosal Immunol 2018[Jan]; 11 (1 ): 199-208 PMID28401938 show ga Influenza A is a highly contagious respiratory virus that causes seasonal epidemics and occasional worldwide pandemics. The primary cause of influenza-related mortality is bacterial superinfection. There are numerous mechanisms by which preceding influenza infection attenuates host defense, allowing for increased susceptibility to bacterial pneumonia. Herein, we demonstrate that influenza inhibits Staphylococcus aureus-induced production of interleukin-33 (IL-33). Restoration of IL-33 during influenza A and methicillin-resistant S. aureus superinfection enhanced bacterial clearance and improved mortality. Innate lymphoid Type 2 cells and alternatively activated macrophages are not required for IL-33-mediated protection during superinfection. We show that IL-33 treatment resulted in neutrophil recruitment to the lung, associated with improved bacterial clearance. These findings identify a novel role for IL-33 in antibacterial host defense at the mucosal barrier. |Animals [MESH] |Bacterial Load [MESH] |Immunity, Innate [MESH] |Influenza A virus/*immunology [MESH] |Interleukin-33/genetics/*metabolism [MESH] |Lymphocytes/*immunology [MESH] |Male [MESH] |Mice [MESH] |Mice, Inbred C57BL [MESH] |Mice, Knockout [MESH] |Neutrophil Infiltration [MESH] |Orthomyxoviridae Infections/*immunology [MESH] |Respiratory Mucosa/*immunology/microbiology/virology [MESH] |Staphylococcal Infections/*immunology [MESH] |Staphylococcus aureus/*immunology [MESH] |Superinfection [MESH]Novel protective mechanism for interleukin-33 at the mucosal barrier d(epmc).pdf DeepDyve Pubget Overpricing