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10.1016/j.ophtha.2017.01.006

http://scihub22266oqcxt.onion/10.1016/j.ophtha.2017.01.006
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suck abstract from ncbi


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pmid28187976
      Ophthalmology 2017 ; 124 (5 ): 697-700
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  • Re-evaluating the Incidence of Idiopathic Intracranial Hypertension in an Era of Increasing Obesity #MMPMID28187976
  • Kilgore KP ; Lee MS ; Leavitt JA ; Mokri B ; Hodge DO ; Frank RD ; Chen JJ
  • Ophthalmology 2017[May]; 124 (5 ): 697-700 PMID28187976 show ga
  • PURPOSE: To re-evaluate the population-based incidence of idiopathic intracranial hypertension (IIH) and to determine if it mirrors the rise in obesity. DESIGN: Retrospective, population-based cohort. PARTICIPANTS: All residents of Olmsted County, Minnesota, diagnosed with IIH between January 1, 1990, and December 31, 2014. METHODS: All cases of IIH were identified using the Rochester Epidemiology Project, which is a record-linkage system of medical records for all patient-physician encounters among Olmsted County, Minnesota, residents. All medical records were reviewed to confirm a diagnosis of IIH. The incidence rates of IIH were compared against the incidence of obesity in Minnesota over the same period. MAIN OUTCOME MEASURES: Incidence of IIH, lumbar puncture opening pressures, and body mass index. RESULTS: There were 63 new cases of IIH, yielding an overall age- and gender-adjusted annual incidence of 1.8 per 100?000 (95% confidence interval, 1.3-2.2) between 1990 and 2014. It increased from 1.0 per 100?000 (1990-2001) to 2.4 per 100?000 (2002-2014; P = 0.007). The incidence of IIH was 3.3 per 100?000 in women and 0.3 per 100?000 in men (P ? 0.001). In obese women 15 to 44 years of age, the incidence was 22.0 per 100?000 compared with 6.8 per 100?000 among all women in the same age group. A strong correlation was observed between IIH incidence rates and obesity rates in Minnesota (R(2) = 0.70, P = 0.008). CONCLUSIONS: The incidence of IIH has increased since 1990, which is highly correlated with the rise in obesity during the same period.
  • |*Intracranial Pressure [MESH]
  • |Adolescent [MESH]
  • |Adult [MESH]
  • |Age Distribution [MESH]
  • |Body Mass Index [MESH]
  • |Female [MESH]
  • |Follow-Up Studies [MESH]
  • |Humans [MESH]
  • |Incidence [MESH]
  • |Male [MESH]
  • |Middle Aged [MESH]
  • |Minnesota/epidemiology [MESH]
  • |Obesity/*complications/epidemiology [MESH]
  • |Pseudotumor Cerebri/*epidemiology/etiology/physiopathology [MESH]
  • |Retrospective Studies [MESH]
  • |Risk Factors [MESH]
  • |Sex Distribution [MESH]


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