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10.1158/2159-8290.CD-17-0550 http://scihub22266oqcxt.onion/10.1158/2159-8290.CD-17-0550 C5630089!5630089!28923911     free     free     free       Cancer+Discov 2017 ; 7 (10): 1069-87 Nephropedia Template TP {{tp|p=28923911|t=2017. How ribosomes translate cancer |pdf=|usr=}}{{28923911}} gab.com Text How ribosomes translate cancer JO: Cancer Discov http://www.kidney.de/pget.php?&tw=1&pmid=28923911 #FOAvip A wealth of novel findings, including congenital ribosomal mutations in ribosomopathies and somatic ribosomal mutations in various cancers, have significantly increased our understanding of the relevance of ribosomes in oncogenesis. Here we explore the growing list of mechanisms by which the ribosome is involved in carcinogenesis ? from the hijacking of ribosomes by oncogenic factors and dysregulated translational control, to the effects of mutations in ribosomal components on cellular metabolism. Of clinical importance, the recent success of RNA polymerase inhibitors highlights the dependence on ?onco-ribosomes? as an Achilles? heel of cancer cells and a promising target for further therapeutic intervention. Twit Text FOAVip How ribosomes translate cancer ????Cancer Discov http://www.kidney.de/pget.php?&tw=1&pmid=28923911 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28923911 #FOAvip English Wikipedia <ref>{{Cite pmid|28923911}}</ref> How ribosomes translate cancer #MMPMID28923911 Sulima SO; Hofman IJ; De Keersmaecker K; Dinman JD Cancer Discov 2017[Oct]; 7 (10): 1069-87 PMID28923911show ga A wealth of novel findings, including congenital ribosomal mutations in ribosomopathies and somatic ribosomal mutations in various cancers, have significantly increased our understanding of the relevance of ribosomes in oncogenesis. Here we explore the growing list of mechanisms by which the ribosome is involved in carcinogenesis ? from the hijacking of ribosomes by oncogenic factors and dysregulated translational control, to the effects of mutations in ribosomal components on cellular metabolism. Of clinical importance, the recent success of RNA polymerase inhibitors highlights the dependence on ?onco-ribosomes? as an Achilles? heel of cancer cells and a promising target for further therapeutic intervention. äHow ribosomes translate cancer (epmc).pdf DeepDyve Pubget Overpricing