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Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Int+J+Mol+Sci 2017 ; 18 (9): ä Nephropedia Template TP
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Overview of ?-Glucans from Laminaria spp : Immunomodulation Properties and Applications on Biologic Models #MMPMID28878139
Bonfim-Mendonça Pde S; Capoci IRG; Tobaldini-Valerio FK; Negri M; Svidzinski TIE
Int J Mol Sci 2017[Sep]; 18 (9): ä PMID28878139show ga
Glucans are a group of glucose polymers that are found in bacteria, algae, fungi, and plants. While their properties are well known, their biochemical and solubility characteristics vary considerably, and glucans obtained from different sources can have different applications. Research has described the bioactivity of ?-glucans extracted from the algae of the Laminaria genus, including in vivo and in vitro studies assessing pro- and anti-inflammatory cytokines, vaccine production, inhibition of cell proliferation, and anti- and pro-oxidant activity. Thus, the objective of this article was to review the potential application of ?-glucans from Laminaria spp. in terms of their immunomodulatory properties, microorganism host interaction, anti-cancer activity and vaccine development.