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10.3390/biomedicines5030049 http://scihub22266oqcxt.onion/10.3390/biomedicines5030049 C5618307!5618307!28805744     free     free     free       Biomedicines 2017 ; 5 (3): ä Nephropedia Template TP {{tp|p=28805744|t=2017. Aptamer Cell-Based Selection: Overview and Advances |pdf=|usr=}}{{28805744}} gab.com Text Aptamer Cell-Based Selection: Overview and Advances JO: Biomedicines http://www.kidney.de/pget.php?&tw=1&pmid=28805744 #FOAvip Aptamers are high affinity single-stranded DNA/RNA molecules, produced by a combinatorial procedure named SELEX (Systematic Evolution of Ligands by Exponential enrichment), that are emerging as promising diagnostic and therapeutic tools. Among selection strategies, procedures using living cells as complex targets (referred as ?cell-SELEX?) have been developed as an effective mean to generate aptamers for heavily modified cell surface proteins, assuring the binding of the target in its native conformation. Here we give an up-to-date overview on cell-SELEX technology, discussing the most recent advances with a particular focus on cancer cell targeting. Examples of the different protocol applications and post-SELEX strategies will be briefly outlined. Twit Text FOAVip Aptamer Cell-Based Selection: Overview and Advances ????Biomedicines http://www.kidney.de/pget.php?&tw=1&pmid=28805744 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28805744 #FOAvip English Wikipedia <ref>{{Cite pmid|28805744}}</ref> Aptamer Cell-Based Selection: Overview and Advances #MMPMID28805744 Catuogno S; Esposito CL Biomedicines 2017[Sep]; 5 (3): ä PMID28805744show ga Aptamers are high affinity single-stranded DNA/RNA molecules, produced by a combinatorial procedure named SELEX (Systematic Evolution of Ligands by Exponential enrichment), that are emerging as promising diagnostic and therapeutic tools. Among selection strategies, procedures using living cells as complex targets (referred as ?cell-SELEX?) have been developed as an effective mean to generate aptamers for heavily modified cell surface proteins, assuring the binding of the target in its native conformation. Here we give an up-to-date overview on cell-SELEX technology, discussing the most recent advances with a particular focus on cancer cell targeting. Examples of the different protocol applications and post-SELEX strategies will be briefly outlined. äAptamer Cell-Based Selection: Overview and Advances (epmc).pdf DeepDyve Pubget Overpricing