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10.1523/ENEURO.0140-17.2017 http://scihub22266oqcxt.onion/10.1523/ENEURO.0140-17.2017 C5617209!5617209!28966978     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       eNeuro 2017 ; 4 (5): ä Nephropedia Template TP {{tp|p=28966978|t=2017. Subthalamic Nucleus Deep Brain Stimulation: Basic Concepts and Novel Perspectives |pdf=|usr=}}{{28966978}} gab.com Text Subthalamic Nucleus Deep Brain Stimulation: Basic Concepts and Novel Perspectives JO: eNeuro http://www.kidney.de/pget.php?&tw=1&pmid=28966978 #FOAvip Over the last decades, extensive basic and clinical knowledge has been acquired on the use of subthalamic nucleus (STN) deep brain stimulation (DBS) for Parkinson?s disease (PD). It is now clear that mechanisms involved in the effects of this therapy are far more complex than previously anticipated. At frequencies commonly used in clinical practice, neural elements may be excited or inhibited and novel dynamic states of equilibrium are reached. Electrode contacts used for chronic DBS in PD are placed near the dorsal border of the nucleus, a highly cellular region. DBS may thus exert its effects by modulating these cells, hyperdirect projections from motor cortical areas, afferent and efferent fibers to the motor STN. Advancements in neuroimaging techniques may allow us to identify these structures optimizing surgical targeting. In this review, we provide an update on mechanisms and the neural elements modulated by STN DBS. Twit Text FOAVip Subthalamic Nucleus Deep Brain Stimulation: Basic Concepts and Novel Perspectives ????eNeuro http://www.kidney.de/pget.php?&tw=1&pmid=28966978 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28966978 #FOAvip English Wikipedia <ref>{{Cite pmid|28966978}}</ref> Subthalamic Nucleus Deep Brain Stimulation: Basic Concepts and Novel Perspectives #MMPMID28966978 Hamani C; Florence G; Heinsen H; Plantinga BR; Temel Y; Uludag K; Alho E; Teixeira MJ; Amaro E; Fonoff ET eNeuro 2017[Sep]; 4 (5): ä PMID28966978show ga Over the last decades, extensive basic and clinical knowledge has been acquired on the use of subthalamic nucleus (STN) deep brain stimulation (DBS) for Parkinson?s disease (PD). It is now clear that mechanisms involved in the effects of this therapy are far more complex than previously anticipated. At frequencies commonly used in clinical practice, neural elements may be excited or inhibited and novel dynamic states of equilibrium are reached. Electrode contacts used for chronic DBS in PD are placed near the dorsal border of the nucleus, a highly cellular region. DBS may thus exert its effects by modulating these cells, hyperdirect projections from motor cortical areas, afferent and efferent fibers to the motor STN. Advancements in neuroimaging techniques may allow us to identify these structures optimizing surgical targeting. In this review, we provide an update on mechanisms and the neural elements modulated by STN DBS. äSubthalamic Nucleus Deep Brain Stimulation: Basic Concepts and Novel P(epmc).pdf DeepDyve Pubget Overpricing