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10.3390/genes8090220 http://scihub22266oqcxt.onion/10.3390/genes8090220 C5615353!5615353!28872594     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Genes+(Basel) 2017 ; 8 (9): ä Nephropedia Template TP {{tp|p=28872594|t=2017. Zebrafish Xenograft: An Evolutionary Experiment in Tumour Biology |pdf=|usr=}}{{28872594}} gab.com Text Zebrafish Xenograft: An Evolutionary Experiment in Tumour Biology JO: Genes (Basel) http://www.kidney.de/pget.php?&tw=1&pmid=28872594 #FOAvip Though the cancer research community has used mouse xenografts for decades more than zebrafish xenografts, zebrafish have much to offer: they are cheap, easy to work with, and the embryonic model is relatively easy to use in high-throughput assays. Zebrafish can be imaged live, allowing us to observe cellular and molecular processes in vivo in real time. Opponents dismiss the zebrafish model due to the evolutionary distance between zebrafish and humans, as compared to mice, but proponents argue for the zebrafish xenograft?s superiority to cell culture systems and its advantages in imaging. This review places the zebrafish xenograft in the context of current views on cancer and gives an overview of how several aspects of this evolutionary disease can be addressed in the zebrafish model. Zebrafish are missing homologs of some human proteins and (of particular interest) several members of the matrix metalloproteinase (MMP) family of proteases, which are known for their importance in tumour biology. This review draws attention to the implicit evolutionary experiment taking place when the molecular ecology of the xenograft host is significantly different than that of the donor. Twit Text FOAVip Zebrafish Xenograft: An Evolutionary Experiment in Tumour Biology ????Genes (Basel) http://www.kidney.de/pget.php?&tw=1&pmid=28872594 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28872594 #FOAvip English Wikipedia <ref>{{Cite pmid|28872594}}</ref> Zebrafish Xenograft: An Evolutionary Experiment in Tumour Biology #MMPMID28872594 Wyatt RA; Trieu NPV; Crawford BD Genes (Basel) 2017[Sep]; 8 (9): ä PMID28872594show ga Though the cancer research community has used mouse xenografts for decades more than zebrafish xenografts, zebrafish have much to offer: they are cheap, easy to work with, and the embryonic model is relatively easy to use in high-throughput assays. Zebrafish can be imaged live, allowing us to observe cellular and molecular processes in vivo in real time. Opponents dismiss the zebrafish model due to the evolutionary distance between zebrafish and humans, as compared to mice, but proponents argue for the zebrafish xenograft?s superiority to cell culture systems and its advantages in imaging. This review places the zebrafish xenograft in the context of current views on cancer and gives an overview of how several aspects of this evolutionary disease can be addressed in the zebrafish model. Zebrafish are missing homologs of some human proteins and (of particular interest) several members of the matrix metalloproteinase (MMP) family of proteases, which are known for their importance in tumour biology. This review draws attention to the implicit evolutionary experiment taking place when the molecular ecology of the xenograft host is significantly different than that of the donor. äZebrafish Xenograft: An Evolutionary Experiment in Tumour Biology (epmc).pdf DeepDyve Pubget Overpricing