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10.3390/bioengineering4030064

http://scihub22266oqcxt.onion/10.3390/bioengineering4030064
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C5615310!5615310!28952543
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suck abstract from ncbi


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pmid28952543      Bioengineering+(Basel) 2017 ; 4 (3): ä
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  • Tumor Microenvironment on a Chip: The Progress and Future Perspective #MMPMID28952543
  • Ahn J; Sei YJ; Jeon NL; Kim Y
  • Bioengineering (Basel) 2017[Sep]; 4 (3): ä PMID28952543show ga
  • Tumors develop in intricate microenvironments required for their sustained growth, invasion, and metastasis. The tumor microenvironment plays a critical role in the malignant or drug resistant nature of tumors, becoming a promising therapeutic target. Microengineered physiological systems capable of mimicking tumor environments are one emerging platform that allows for quantitative and reproducible characterization of tumor responses with pathophysiological relevance. This review highlights the recent advancements of engineered tumor microenvironment systems that enable the unprecedented mechanistic examination of cancer progression and metastasis. We discuss the progress and future perspective of these microengineered biomimetic approaches for anticancer drug prescreening applications.
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