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Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 J+Comput+Biol 2017 ; 24 (9): 895-905 Nephropedia Template TP
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MOTIFSIM 2 1: An Enhanced Software Platform for Detecting Similarity in Multiple DNA Motif Data Sets #MMPMID28632401
Tran NTL; Huang CH
J Comput Biol 2017[Sep]; 24 (9): 895-905 PMID28632401show ga
Finding binding site motifs plays an important role in bioinformatics as it reveals the transcription factors that control the gene expression. The development for motif finders has flourished in the past years with many tools have been introduced to the research community. Although these tools possess exceptional features for detecting motifs, they report different results for an identical data set. Hence, using multiple tools is recommended because motifs reported by several tools are likely biologically significant. However, the results from multiple tools need to be compared for obtaining common significant motifs. MOTIFSIM web tool and command-line tool were developed for this purpose. In this work, we present several technical improvements as well as additional features to further support the motif analysis in our new release MOTIFSIM 2.1.