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10.1186/s13059-017-1309-9 http://scihub22266oqcxt.onion/10.1186/s13059-017-1309-9 C5607848!5607848!28934976     free     free     free Deprecated: Implicit conversion from float 225.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 225.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Genome+Biol 2017 ; 18 (ä): ä Nephropedia Template TP {{tp|p=28934976|t=2017. DESMAN: a new tool for de novo extraction of strains from metagenomes |pdf=|usr=}}{{28934976}} gab.com Text DESMAN: a new tool for de novo extraction of strains from metagenomes JO: Genome Biol http://www.kidney.de/pget.php?&tw=1&pmid=28934976 #FOAvip We introduce DESMAN for De novo Extraction of Strains from Metagenomes. Large multi-sample metagenomes are being generated but strain variation results in fragmentary co-assemblies. Current algorithms can bin contigs into metagenome-assembled genomes but are unable to resolve strain-level variation. DESMAN identifies variants in core genes and uses co-occurrence across samples to link variants into haplotypes and abundance profiles. These are then searched for against non-core genes to determine the accessory genome of each strain. We validated DESMAN on a complex 50-species 210-genome 96-sample synthetic mock data set and then applied it to the Tara Oceans microbiome.Electronic supplementary material: The online version of this article (doi:10.1186/s13059-017-1309-9) contains supplementary material, which is available to authorized users. Twit Text FOAVip DESMAN: a new tool for de novo extraction of strains from metagenomes ????Genome Biol http://www.kidney.de/pget.php?&tw=1&pmid=28934976 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28934976 #FOAvip English Wikipedia <ref>{{Cite pmid|28934976}}</ref> DESMAN: a new tool for de novo extraction of strains from metagenomes #MMPMID28934976 Quince C; Delmont TO; Raguideau S; Alneberg J; Darling AE; Collins G; Eren AM Genome Biol 2017[]; 18 (ä): ä PMID28934976show ga We introduce DESMAN for De novo Extraction of Strains from Metagenomes. Large multi-sample metagenomes are being generated but strain variation results in fragmentary co-assemblies. Current algorithms can bin contigs into metagenome-assembled genomes but are unable to resolve strain-level variation. DESMAN identifies variants in core genes and uses co-occurrence across samples to link variants into haplotypes and abundance profiles. These are then searched for against non-core genes to determine the accessory genome of each strain. We validated DESMAN on a complex 50-species 210-genome 96-sample synthetic mock data set and then applied it to the Tara Oceans microbiome.Electronic supplementary material: The online version of this article (doi:10.1186/s13059-017-1309-9) contains supplementary material, which is available to authorized users. äDESMAN: a new tool for de novo extraction of strains from metagenomes (epmc).pdf DeepDyve Pubget Overpricing