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10.1093/nar/gkw131 http://scihub22266oqcxt.onion/10.1093/nar/gkw131 C5603959!5603959!26939888     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Nucleic+Acids+Res 2016 ; 44 (11): 5148-60 Nephropedia Template TP {{tp|p=26939888|t=2016. Chromosome intermingling?the physical basis of chromosome organization in differentiated cells |pdf=|usr=}}{{26939888}} gab.com Text Chromosome intermingling the physical basis of chromosome organization in differentiated cells JO: Nucleic Acids Res http://www.kidney.de/pget.php?&tw=1&pmid=26939888 #FOAvip Chromosome territories (CTs) in higher eukaryotes occupy tissue-specific non-random three-dimensional positions in the interphase nucleus. To understand the mechanisms underlying CT organization, we mapped CT position and transcriptional changes in undifferentiated embryonic stem (ES) cells, during early onset of mouse ES cell differentiation and in terminally differentiated NIH3T3 cells. We found chromosome intermingling volume to be a reliable CT surface property, which can be used to define CT organization. Our results show a correlation between the transcriptional activity of chromosomes and heterologous chromosome intermingling volumes during differentiation. Furthermore, these regions were enriched in active RNA polymerase and other histone modifications in the differentiated states. These findings suggest a correlation between the evolution of transcription program in modifying CT architecture in undifferentiated stem cells. This leads to the formation of functional CT surfaces, which then interact to define the three-dimensional CT organization during differentiation. Twit Text FOAVip Chromosome intermingling the physical basis of chromosome organization in differentiated cells ????Nucleic Acids Res http://www.kidney.de/pget.php?&tw=1&pmid=26939888 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26939888 #FOAvip English Wikipedia <ref>{{Cite pmid|26939888}}</ref> Chromosome intermingling?the physical basis of chromosome organization in differentiated cells #MMPMID26939888 Maharana S; Iyer KV; Jain N; Nagarajan M; Wang Y; Shivashankar GV Nucleic Acids Res 2016[Jun]; 44 (11): 5148-60 PMID26939888show ga Chromosome territories (CTs) in higher eukaryotes occupy tissue-specific non-random three-dimensional positions in the interphase nucleus. To understand the mechanisms underlying CT organization, we mapped CT position and transcriptional changes in undifferentiated embryonic stem (ES) cells, during early onset of mouse ES cell differentiation and in terminally differentiated NIH3T3 cells. We found chromosome intermingling volume to be a reliable CT surface property, which can be used to define CT organization. Our results show a correlation between the transcriptional activity of chromosomes and heterologous chromosome intermingling volumes during differentiation. Furthermore, these regions were enriched in active RNA polymerase and other histone modifications in the differentiated states. These findings suggest a correlation between the evolution of transcription program in modifying CT architecture in undifferentiated stem cells. This leads to the formation of functional CT surfaces, which then interact to define the three-dimensional CT organization during differentiation. äChromosome intermingling?the physical basis of chromosome organization(epmc).pdf DeepDyve Pubget Overpricing