Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 267.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\28714092
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 J+Anat
2017 ; 231
(4
): 634-637
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Serial block-face scanning electron microscopy of erythrocytes protruding through
the human placental syncytiotrophoblast
#MMPMID28714092
Palaiologou E
; Goggin P
; Chatelet DS
; Lofthouse EM
; Torrens C
; Sengers BG
; Cleal JK
; Page A
; Lewis RM
J Anat
2017[Oct]; 231
(4
): 634-637
PMID28714092
show ga
The syncytiotrophoblast forms a continuous barrier between the maternal and fetal
circulations. Here we present a serial block-face scanning electron microscopy
(SBFSEM) study, based on a single image stack, showing pooling of fetal blood
underneath a region of stretched syncytiotrophoblast that has become detached
from the basement membrane. Erythrocytes are protruding from discrete holes in
the syncytiotrophoblast suggesting that, under specific circumstances, the
syncytiotrophoblast may be permeable to fetal cells. This observation represents
a pathological process but it poses questions about the physical properties and
permeability of the syncytiotrophoblast and may represent an early stage in the
formation of fibrin deposits in areas of syncytial denudation. This study also
illustrates how the 3D images generated by SBFSEM allow the interpretation of
structures that could not be understood from a single histological section.