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10.1016/j.bbrep.2015.09.022 http://scihub22266oqcxt.onion/10.1016/j.bbrep.2015.09.022 C5600415!5600415!28955851     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Biochem+Biophys+Rep 2016 ; 5 (ä): 439-47 Nephropedia Template TP {{tp|p=28955851|t=2016. Complicated behavior of G-quadruplexes and evaluating G-quadruplexes ligands in various systems mimicking cellular circumstance |pdf=|usr=}}{{28955851}} gab.com Text Complicated behavior of G-quadruplexes and evaluating G-quadruplexes ligands in various systems mimicking cellular circumstance JO: Biochem Biophys Rep http://www.kidney.de/pget.php?&tw=1&pmid=28955851 #FOAvip Environments surrounding G-rich sequences remarkably affect the conformations of these structures. A proper evaluation system mimicking the crowded environment in a cell with macromolecules should be developed to perform structural and functional studies on G-quadruplexes. In this study, the topology and stability of a G-quadruplex formed by human telomeric repeat sequences were investigated in a macromolecule-crowded environment created by polyethylene glycol 200 (PEG200), tumor cell extract, and Xenopus laevis egg extract. The interactions between small molecules and telomeric G-quadruplexes were also evaluated in the different systems. The results suggested that the actual behavior of G-quadruplex structures in cells extract is quite different from that in the PEG crowding system, and proteins or other factors in extracts might play a very important role in G-quadruplex structures. Twit Text FOAVip Complicated behavior of G-quadruplexes and evaluating G-quadruplexes ligands in various systems mimicking cellular circumstance ????Biochem Biophys Rep http://www.kidney.de/pget.php?&tw=1&pmid=28955851 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28955851 #FOAvip English Wikipedia <ref>{{Cite pmid|28955851}}</ref> Complicated behavior of G-quadruplexes and evaluating G-quadruplexes ligands in various systems mimicking cellular circumstance #MMPMID28955851 Wang SK; Su HF; Gu YC; Lin SL; Tan JH; Huang ZS; Ou TM Biochem Biophys Rep 2016[Mar]; 5 (ä): 439-47 PMID28955851show ga Environments surrounding G-rich sequences remarkably affect the conformations of these structures. A proper evaluation system mimicking the crowded environment in a cell with macromolecules should be developed to perform structural and functional studies on G-quadruplexes. In this study, the topology and stability of a G-quadruplex formed by human telomeric repeat sequences were investigated in a macromolecule-crowded environment created by polyethylene glycol 200 (PEG200), tumor cell extract, and Xenopus laevis egg extract. The interactions between small molecules and telomeric G-quadruplexes were also evaluated in the different systems. The results suggested that the actual behavior of G-quadruplex structures in cells extract is quite different from that in the PEG crowding system, and proteins or other factors in extracts might play a very important role in G-quadruplex structures. äComplicated behavior of G-quadruplexes and evaluating G-quadruplexes (epmc).pdf DeepDyve Pubget Overpricing