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10.1016/j.bbrep.2016.02.002 http://scihub22266oqcxt.onion/10.1016/j.bbrep.2016.02.002 C5600343!5600343!28955848     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Biochem+Biophys+Rep 2016 ; 5 (ä): 401-7 Nephropedia Template TP {{tp|p=28955848|t=2016. Soluble ST2 suppresses the effect of interleukin-33 on lung type 2 innate lymphoid cells |pdf=|usr=}}{{28955848}} gab.com Text Soluble ST2 suppresses the effect of interleukin-33 on lung type 2 innate lymphoid cells JO: Biochem Biophys Rep http://www.kidney.de/pget.php?&tw=1&pmid=28955848 #FOAvip Type 2 innate lymphoid cells (ILC2) in lungs produce interleukin (IL)-5 and IL-13 in response to IL-33 and may contribute to the development of allergic diseases such as asthma. However, little is known about negative regulators and effective inhibitors controlling ILC2 function. Here, we show that soluble ST2, a member of the IL-1 receptor family, suppresses the effect of IL-33 on lung ILC2 in vitro. Stimulation with IL-33 to naïve ILC2 induced morphological change and promoted cell proliferation. In addition, IL-33 upregulated expression of cell surface molecules including IL-33 receptor and induced production of IL-5 and IL-13, but not IL-4. Pretreatment with soluble ST2 suppressed IL-33-mediated responses of ILC2. The results suggest that soluble ST2 acts as a decoy receptor for IL-33 and protects ILC2 from IL-33 stimulation. Twit Text FOAVip Soluble ST2 suppresses the effect of interleukin-33 on lung type 2 innate lymphoid cells ????Biochem Biophys Rep http://www.kidney.de/pget.php?&tw=1&pmid=28955848 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28955848 #FOAvip English Wikipedia <ref>{{Cite pmid|28955848}}</ref> Soluble ST2 suppresses the effect of interleukin-33 on lung type 2 innate lymphoid cells #MMPMID28955848 Hayakawa H; Hayakawa M; Tominaga Si Biochem Biophys Rep 2016[Mar]; 5 (ä): 401-7 PMID28955848show ga Type 2 innate lymphoid cells (ILC2) in lungs produce interleukin (IL)-5 and IL-13 in response to IL-33 and may contribute to the development of allergic diseases such as asthma. However, little is known about negative regulators and effective inhibitors controlling ILC2 function. Here, we show that soluble ST2, a member of the IL-1 receptor family, suppresses the effect of IL-33 on lung ILC2 in vitro. Stimulation with IL-33 to naïve ILC2 induced morphological change and promoted cell proliferation. In addition, IL-33 upregulated expression of cell surface molecules including IL-33 receptor and induced production of IL-5 and IL-13, but not IL-4. Pretreatment with soluble ST2 suppressed IL-33-mediated responses of ILC2. The results suggest that soluble ST2 acts as a decoy receptor for IL-33 and protects ILC2 from IL-33 stimulation. äSoluble ST2 suppresses the effect of interleukin-33 on lung type 2 inn(epmc).pdf DeepDyve Pubget Overpricing