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10.1038/nmeth.4197

http://scihub22266oqcxt.onion/10.1038/nmeth.4197
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C5600148!5600148!28263959
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suck abstract from ncbi


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pmid28263959      Nat+Methods 2017 ; 14 (4): 417-9
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  • Salmon: fast and bias-aware quantification of transcript expression using dual-phase inference #MMPMID28263959
  • Patro R; Duggal G; Love MI; Irizarry RA; Kingsford C
  • Nat Methods 2017[Apr]; 14 (4): 417-9 PMID28263959show ga
  • We introduce Salmon, a method for quantifying transcript abundance from RNA-seq reads that is accurate and fast. Salmon is the first transcriptome-wide quantifier to correct for fragment GC content bias, which we demonstrate substantially improves the accuracy of abundance estimates and the reliability of subsequent differential expression analysis. Salmon combines a new dual-phase parallel inference algorithm and feature-rich bias models with an ultra-fast read mapping procedure.
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