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2017 ; 22
(9
): 1015-1019
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The Evolution of Clinical Trials in Oncology: Defining Who Benefits from New
Drugs Using Innovative Study Designs
#MMPMID28620092
Goldberg RM
; Wei L
; Fernandez S
Oncologist
2017[Sep]; 22
(9
): 1015-1019
PMID28620092
show ga
Historically, advocates of randomized drug treatment trials in oncology
contributed to the changing paradigm for testing cancer treatments in the U.S.,
which led to global efforts to generate evidence of promise in preclinical model
systems and translate those findings into improved patient outcomes. In the age
of genomic medicine, the challenge to speed the evolution of how clinical trials
are conducted in patients with cancer continues.