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10.1016/j.jmb.2016.02.024 http://scihub22266oqcxt.onion/10.1016/j.jmb.2016.02.024 C5599101!5599101!26946034     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Mol+Biol 2016 ; 428 (9 Pt A): 1700-13 Nephropedia Template TP {{tp|p=26946034|t=2016. Mechanistically Dissecting Autophagy: Insights from In Vitro Reconstitution |pdf=|usr=}}{{26946034}} gab.com Text Mechanistically Dissecting Autophagy: Insights from In Vitro Reconstitution JO: J Mol Biol http://www.kidney.de/pget.php?&tw=1&pmid=26946034 #FOAvip Autophagy is a fundamental cellular mechanism responsible for bulk turnover of cytoplasmic components. It is broadly related to many cellular activities, physiological processes, and pathological conditions. Autophagy entails a spatiotemporal interaction between cytosolic factors and membranes that are remodeled to encapsulate autophagic cargo within an autophagosome. Although majority of the factors [autophagy-related gene (Atg) proteins] involved in autophagy have been identified by genetic studies, the mechanism accounting for how these factors act upon the membrane to remodel it and efficiently recruit cargo for degradation is unclear. In vitro reconstitution of several different aspects of autophagy has provided important insights into the understanding of the mechanistic details underlying autophagic membrane remodeling and cargo recruitment. Here, we highlight these efforts toward studying autophagy through in vitro approaches. Twit Text FOAVip Mechanistically Dissecting Autophagy: Insights from In Vitro Reconstitution ????J Mol Biol http://www.kidney.de/pget.php?&tw=1&pmid=26946034 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26946034 #FOAvip English Wikipedia <ref>{{Cite pmid|26946034}}</ref> Mechanistically Dissecting Autophagy: Insights from In Vitro Reconstitution #MMPMID26946034 Brier LW; Zhang M; Ge L J Mol Biol 2016[May]; 428 (9 Pt A): 1700-13 PMID26946034show ga Autophagy is a fundamental cellular mechanism responsible for bulk turnover of cytoplasmic components. It is broadly related to many cellular activities, physiological processes, and pathological conditions. Autophagy entails a spatiotemporal interaction between cytosolic factors and membranes that are remodeled to encapsulate autophagic cargo within an autophagosome. Although majority of the factors [autophagy-related gene (Atg) proteins] involved in autophagy have been identified by genetic studies, the mechanism accounting for how these factors act upon the membrane to remodel it and efficiently recruit cargo for degradation is unclear. In vitro reconstitution of several different aspects of autophagy has provided important insights into the understanding of the mechanistic details underlying autophagic membrane remodeling and cargo recruitment. Here, we highlight these efforts toward studying autophagy through in vitro approaches. äMechanistically Dissecting Autophagy: Insights from In Vitro Reconstit(epmc).pdf DeepDyve Pubget Overpricing