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2017 ; 65
(8
): 758-760
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Aflibercept for recurrent or recalcitrant polypoidal choroidal vasculopathy in
Indian eyes: Early experience
#MMPMID28820169
Bansal A
; Bhende M
; Sharma T
; Bhende P
; Mukherjee S
Indian J Ophthalmol
2017[Aug]; 65
(8
): 758-760
PMID28820169
show ga
Treatment guidelines for symptomatic polypoidal choroidal vasculopathy (PCV) have
been described, but the management of recurrent or recalcitrant PCV is a
challenge. The newer anti-vascular endothelial growth factor: aflibercept has
shown promise in the treatment of both treatment naive and recalcitrant PCV in
studies outside India. We present the minimum 6 months results of intravitreal
aflibercept in recurrent and recalcitrant PCV in Indian eyes after multiple
injections of bevacizumab/ranibizumab with or without photodynamic therapy. Of 10
eyes, 7 resolved of which 4 recurred needing continued aflibercept. Three of the
ten eyes did not show a response. To the best of our knowledge, this is the first
report from India in this challenging situation.