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2017 ; 9
(8
): 2013-2022
Nephropedia Template TP
gab.com Text
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English Wikipedia
Discerning the Origins of the Negritos, First Sundaland People: Deep Divergence
and Archaic Admixture
#MMPMID28854687
Jinam TA
; Phipps ME
; Aghakhanian F
; Majumder PP
; Datar F
; Stoneking M
; Sawai H
; Nishida N
; Tokunaga K
; Kawamura S
; Omoto K
; Saitou N
Genome Biol Evol
2017[Aug]; 9
(8
): 2013-2022
PMID28854687
show ga
Human presence in Southeast Asia dates back to at least 40,000?years ago, when
the current islands formed a continental shelf called Sundaland. In the
Philippine Islands, Peninsular Malaysia, and Andaman Islands, there exist
indigenous groups collectively called Negritos whose ancestry can be traced to
the "First Sundaland People." To understand the relationship between these
Negrito groups and their demographic histories, we generated genome-wide single
nucleotide polymorphism data in the Philippine Negritos and compared them with
existing data from other populations. Phylogenetic tree analyses show that
Negritos are basal to other East and Southeast Asians, and that they diverged
from West Eurasians at least 38,000?years ago. We also found relatively high
traces of Denisovan admixture in the Philippine Negritos, but not in the
Malaysian and Andamanese groups, suggesting independent introgression and/or
parallel losses involving Denisovan introgressed regions. Shared genetic loci
between all three Negrito groups could be related to skin pigmentation, height,
facial morphology and malarial resistance. These results show the unique status
of Negrito groups as descended from the First Sundaland People.