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2017 ; 7
(1
): 11452
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Brain damage and behavioural disorders in fish induced by plastic nanoparticles
delivered through the food chain
#MMPMID28904346
Mattsson K
; Johnson EV
; Malmendal A
; Linse S
; Hansson LA
; Cedervall T
Sci Rep
2017[Sep]; 7
(1
): 11452
PMID28904346
show ga
The tremendous increases in production of plastic materials has led to an
accumulation of plastic pollution worldwide. Many studies have addressed the
physical effects of large-sized plastics on organisms, whereas few have focused
on plastic nanoparticles, despite their distinct chemical, physical and
mechanical properties. Hence our understanding of their effects on ecosystem
function, behaviour and metabolism of organisms remains elusive. Here we
demonstrate that plastic nanoparticles reduce survival of aquatic zooplankton and
penetrate the blood-to-brain barrier in fish and cause behavioural disorders.
Hence, for the first time, we uncover direct interactions between plastic
nanoparticles and brain tissue, which is the likely mechanism behind the observed
behavioural disorders in the top consumer. In a broader perspective, our findings
demonstrate that plastic nanoparticles are transferred up through a food chain,
enter the brain of the top consumer and affect its behaviour, thereby severely
disrupting the function of natural ecosystems.