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10.1038/s41598-017-11838-1 http://scihub22266oqcxt.onion/10.1038/s41598-017-11838-1 C5597578!5597578 !28904360     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=28904360 &cmd=llinks): Failed to open stream: HTTP request failed! 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Comparison of prognostic, clinical, and renal histopathological characteristics of overlapping idiopathic membranous nephropathy and IgA nephropathy versus idiopathic membranous nephropathy |pdf=|usr=}}{{28904360 }} gab.com Text Comparison of prognostic, clinical, and renal histopathological characteristics of overlapping idiopathic membranous nephropathy and IgA nephropathy versus idiopathic membranous nephropathy JO: Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=28904360 #FOAvip Overlapping idiopathic membranous nephropathy (IMN) and immunoglobulin A nephropathy (IgAN) is rare. This study aims to investigate the unique prognostic, clinical, and renal histopathological characteristics of IMN+IgAN. This retrospective observational study included 73 consecutive cases of IMN+IgAN and 425 cases of IMN treated between September 2006 and November 2015. Prognostic and baseline clinical and histopathological data were compared between the two patient groups. Poor prognostic events included a permanent 50% reduction in eGFR, end-stage renal disease, and all-cause mortality. Renal histopathology demonstrated that the patients with IMN+IgAN presented with significantly increased mesangial cell proliferation and matrix expansion, increased inflammatory cell infiltration, and higher proportions of arteriole hyalinosis and lesions than the patients with IMN (all P?<?0.05). Kaplan-Meier analysis showed that the patients with IMN+IgAN had significantly higher cumulative incidence rates of partial or complete remission (PR or CR, P?=?0.0085). Multivariate Cox model analysis revealed that old age at biopsy and high baseline serum creatinine and uric acid levels were significantly associated with poor prognosis (all P?<?0.05), and increased IgA expression correlated significantly with PR or CR (P?<?0.05). The present study found that overlapping IMN and IgAN presents with unique renal histopathology and appears not to cause a poorer prognosis than IMN. Twit Text FOAVip Comparison of prognostic, clinical, and renal histopathological characteristics of overlapping idiopathic membranous nephropathy and IgA nephropathy versus idiopathic membranous nephropathy ????Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=28904360 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28904360 #FOAvip English Wikipedia <ref>{{Cite pmid|28904360 }}</ref> Comparison of prognostic, clinical, and renal histopathological characteristics of overlapping idiopathic membranous nephropathy and IgA nephropathy versus idiopathic membranous nephropathy #MMPMID28904360 Chen X ; Chen Y ; Shi K ; Lv Y ; Tong H ; Zhao G ; Chen C ; Chen B ; Li D ; Lu Z Sci Rep 2017[Sep]; 7 (1 ): 11468 PMID28904360 show ga Overlapping idiopathic membranous nephropathy (IMN) and immunoglobulin A nephropathy (IgAN) is rare. This study aims to investigate the unique prognostic, clinical, and renal histopathological characteristics of IMN+IgAN. This retrospective observational study included 73 consecutive cases of IMN+IgAN and 425 cases of IMN treated between September 2006 and November 2015. Prognostic and baseline clinical and histopathological data were compared between the two patient groups. Poor prognostic events included a permanent 50% reduction in eGFR, end-stage renal disease, and all-cause mortality. Renal histopathology demonstrated that the patients with IMN+IgAN presented with significantly increased mesangial cell proliferation and matrix expansion, increased inflammatory cell infiltration, and higher proportions of arteriole hyalinosis and lesions than the patients with IMN (all P? |Adult [MESH] |Biomarkers [MESH] |Biopsy [MESH] |Comorbidity [MESH] |Female [MESH] |Fluorescent Antibody Technique [MESH] |Glomerulonephritis, IGA/*diagnosis/etiology/metabolism/*mortality [MESH] |Glomerulonephritis, Membranous/*diagnosis/etiology/metabolism/*mortality [MESH] |Humans [MESH] |Immunohistochemistry [MESH] |Kaplan-Meier Estimate [MESH] |Kidney Function Tests [MESH] |Kidney/*pathology [MESH] |Male [MESH] |Mesangial Cells/metabolism/pathology/ultrastructure [MESH] |Middle Aged [MESH]Comparison of prognostic, clinical, and renal histopathological charac(epmc).pdf DeepDyve Pubget Overpricing