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10.4103/jomfp.JOMFP_60_17 http://scihub22266oqcxt.onion/10.4103/jomfp.JOMFP_60_17 C5596675!5596675!28932034     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=28932034&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Oral+Maxillofac+Pathol 2017 ; 21 (2): 244-51 Nephropedia Template TP {{tp|p=28932034|t=2017. Alteration of cellular metabolism in cancer cells and its therapeutic prospects |pdf=|usr=}}{{28932034}} gab.com Text Alteration of cellular metabolism in cancer cells and its therapeutic prospects JO: J Oral Maxillofac Pathol http://www.kidney.de/pget.php?&tw=1&pmid=28932034 #FOAvip Transformation of a normal cell into a cancerous phenotype is essentially backed by genetic mutations that trigger several oncogenic signaling pathways. These signaling pathways rewire the cellular metabolism to meet the bioenergetic and biomass requirement of proliferating cell, which is different from a quiescent cell. Although the change of metabolism in a cancer cell was observed and studied in the mid-20th century, it was not adequate to explain oncogenesis. Now, equipped with a revolution of oncogenes, we have a genetic basis to explain the transformation. Through several studies, it is clear now that such metabolic alterations not only promote cancer progression but also contribute to the chemoresistance of cancer. Targeting specific enzymes and combinations of enzymes can improve the efficacy of cancer therapy and help to overcome the therapeutic resistance. Twit Text FOAVip Alteration of cellular metabolism in cancer cells and its therapeutic prospects ????J Oral Maxillofac Pathol http://www.kidney.de/pget.php?&tw=1&pmid=28932034 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28932034 #FOAvip English Wikipedia <ref>{{Cite pmid|28932034}}</ref> Alteration of cellular metabolism in cancer cells and its therapeutic prospects #MMPMID28932034 Biswal BN; Das SN; Das BK; Rath R J Oral Maxillofac Pathol 2017[May]; 21 (2): 244-51 PMID28932034show ga Transformation of a normal cell into a cancerous phenotype is essentially backed by genetic mutations that trigger several oncogenic signaling pathways. These signaling pathways rewire the cellular metabolism to meet the bioenergetic and biomass requirement of proliferating cell, which is different from a quiescent cell. Although the change of metabolism in a cancer cell was observed and studied in the mid-20th century, it was not adequate to explain oncogenesis. Now, equipped with a revolution of oncogenes, we have a genetic basis to explain the transformation. Through several studies, it is clear now that such metabolic alterations not only promote cancer progression but also contribute to the chemoresistance of cancer. Targeting specific enzymes and combinations of enzymes can improve the efficacy of cancer therapy and help to overcome the therapeutic resistance. äAlteration of cellular metabolism in cancer cells and its therapeutic (epmc).pdf DeepDyve Pubget Overpricing