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Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Intern+Med 2017 ; 56 (16): 2205-11 Nephropedia Template TP
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Successful Treatment of TAFRO Syndrome with Tocilizumab, Prednisone, and Cyclophosphamide #MMPMID28781319
Kikuchi T; Shimizu T; Toyama T; Abe R; Okamoto S
Intern Med 2017[Aug]; 56 (16): 2205-11 PMID28781319show ga
TAFRO syndrome is a rare systemic inflammatory disease characterized by thrombocytopenia, pleural effusion, fever, renal dysfunction, reticulin fibrosis of the bone marrow, and organomegaly. The clinical course varies significantly among patients. However, the prognosis is usually dismal in patients with severe TAFRO syndrome, and no optimal treatment has yet been established. We herein describe the first case of TAFRO syndrome, which was successfully treated with combination therapy consisting of tocilizumab, prednisone, and cyclophosphamide.