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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Int+J+Ophthalmol
2017 ; 10
(9
): 1402-1406
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Optical coherence tomography angiography of optic disc perfusion in non-arteritic
anterior ischemic optic neuropathy
#MMPMID28944200
Ling JW
; Yin X
; Lu QY
; Chen YY
; Lu PR
Int J Ophthalmol
2017[]; 10
(9
): 1402-1406
PMID28944200
show ga
AIM: To compare the optic disc blood flow of non-arteritic ischemic optic
neuropathy (NAION) eyes with normal eyes. METHODS: The optic disc blood flow
densities of diagnosed non-acute phase NAION eyes (21 eyes, 14 individuals) and
normal eyes (19 eyes, 12 individuals) were detected via Optovue optical coherence
tomography angiography (OCTA). The optic disc blood flow was measured via Image J
software. Correlations between optic disc perfusion and visual function variables
were assessed by linear regression analysis. RESULTS: The average percentage of
the optic disc non-perfusion areas in the non-acute phase NAION patients
(17.84%±6.18%) was increased, when compared to the normal control eyes
(8.61%±1.65%), and the difference was statistically significant (P<0.01).
Moreover, there was a proportional correlation between the visual field mean
defect (MD) and the optic disc non-perfusion area percentage, and the
relationship was statistically significant (t=3.65, P<0.01, R(2)=0.4118). In
addition, the critical correlation between the best corrected visual acuity
(BCVA) and the optic disc non-perfusion area percentage was statistically
significant (t=4.32, P<0.01, R(2)=0.4957). CONCLUSION: The optic disc
non-perfusion area percentages detected via OCTA in NAION eyes were significantly
increased when compared with the normal eyes. Both the BCVA and MD were
correlated with the optic disc flow detected, revealing that OCTA may be valuable
in the diagnosis and estimation of NAION.