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10.3389/fcimb.2017.00398 http://scihub22266oqcxt.onion/10.3389/fcimb.2017.00398 C5596086!5596086!28944217     free     free     free Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 263.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 263.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 263.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 263.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 263.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 296.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 296.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Front+Cell+Infect+Microbiol 2017 ; 7 (ä): ä Nephropedia Template TP {{tp|p=28944217|t=2017. Activation of iNKT Cells Prevents Salmonella-Enterocolitis and Salmonella-Induced Reactive Arthritis by Downregulating IL-17-Producing ??T Cells |pdf=|usr=}}{{28944217}} gab.com Text Activation of iNKT Cells Prevents Salmonella-Enterocolitis and Salmonella-Induced Reactive Arthritis by Downregulating IL-17-Producing T Cells JO: Front Cell Infect Microbiol http://www.kidney.de/pget.php?&tw=1&pmid=28944217 #FOAvip Reactive arthritis (ReA) is an inflammatory condition of the joints that arises following an infection. Salmonella enterocolitis is one of the most common infections leading to ReA. Although the pathogenesis remains unclear, it is known that IL-17 plays a pivotal role in the development of ReA. IL-17-producers cells are mainly Th17, iNKT, and ??T lymphocytes. It is known that iNKT cells regulate the development of Th17 lineage. Whether iNKT cells also regulate ??T lymphocytes differentiation is unknown. We found that iNKT cells play a protective role in ReA. BALB/c J?18?/? mice suffered a severe Salmonella enterocolitis, a 3.5-fold increase in IL-17 expression and aggravated inflammation of the synovial membrane. On the other hand, activation of iNKT cells with ?-GalCer abrogated IL-17 response to Salmonella enterocolitis and prevented intestinal and joint tissue damage. Moreover, the anti-inflammatory effect of ?-GalCer was related to a drop in the proportion of IL-17-producing ??T lymphocytes (IL17-??Tcells) rather than to a decrease in Th17 cells. In summary, we here show that iNKT cells play a protective role against Salmonella-enterocolitis and Salmonella-induced ReA by downregulating IL17-??Tcells. Twit Text FOAVip Activation of iNKT Cells Prevents Salmonella-Enterocolitis and Salmonella-Induced Reactive Arthritis by Downregulating IL-17-Producing T Cells ????Front Cell Infect Microbiol http://www.kidney.de/pget.php?&tw=1&pmid=28944217 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28944217 #FOAvip English Wikipedia <ref>{{Cite pmid|28944217}}</ref> Activation of iNKT Cells Prevents Salmonella-Enterocolitis and Salmonella-Induced Reactive Arthritis by Downregulating IL-17-Producing ??T Cells #MMPMID28944217 Noto Llana M; Sarnacki SH; Morales AL; Aya Castañeda Mdel R; Giacomodonato MN; Blanco G; Cerquetti MC Front Cell Infect Microbiol 2017[]; 7 (ä): ä PMID28944217show ga Reactive arthritis (ReA) is an inflammatory condition of the joints that arises following an infection. Salmonella enterocolitis is one of the most common infections leading to ReA. Although the pathogenesis remains unclear, it is known that IL-17 plays a pivotal role in the development of ReA. IL-17-producers cells are mainly Th17, iNKT, and ??T lymphocytes. It is known that iNKT cells regulate the development of Th17 lineage. Whether iNKT cells also regulate ??T lymphocytes differentiation is unknown. We found that iNKT cells play a protective role in ReA. BALB/c J?18?/? mice suffered a severe Salmonella enterocolitis, a 3.5-fold increase in IL-17 expression and aggravated inflammation of the synovial membrane. On the other hand, activation of iNKT cells with ?-GalCer abrogated IL-17 response to Salmonella enterocolitis and prevented intestinal and joint tissue damage. Moreover, the anti-inflammatory effect of ?-GalCer was related to a drop in the proportion of IL-17-producing ??T lymphocytes (IL17-??Tcells) rather than to a decrease in Th17 cells. In summary, we here show that iNKT cells play a protective role against Salmonella-enterocolitis and Salmonella-induced ReA by downregulating IL17-??Tcells. äActivation of iNKT Cells Prevents Salmonella-Enterocolitis and Salmone(epmc).pdf DeepDyve Pubget Overpricing