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10.1007/s40134-017-0256-2

http://scihub22266oqcxt.onion/10.1007/s40134-017-0256-2
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C5594046!5594046!28959504
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suck abstract from ncbi


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pmid28959504      Curr+Radiol+Rep 2017 ; 5 (11): ä
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  • Imaging Features of Toxicities by Immune Checkpoint Inhibitors in Cancer Therapy #MMPMID28959504
  • Widmann G; Nguyen VA; Plaickner J; Jaschke W
  • Curr Radiol Rep 2017[]; 5 (11): ä PMID28959504show ga
  • Purpose of review: With the increasing use of immune checkpoint inhibitors in cancer therapy radiographic profiling of frequent and serious immune-related adverse events (irAEs) becomes more relevant. This article reviews imaging features of irAEs induced by the anti-CTLA-4 and anti-PD-1 antibodies ipilimumab, nivolumab and pembrolizumab. Recent findings: Important radiological manifestations are immune-related colitis, hepatitis, pancreatitis, hypophysitis, pneumonitis, arthritis and sarcoid-like lymphadenopathy. Typical imaging features are summarized and compared with other relevant differential diagnoses. Summary: Early diagnosis and appropriate therapeutic decisions are required for a successful treatment of irAEs. In addition to staging and follow-up imaging, identification and monitoring of adverse events becomes an important radiologic aspect in oncologic care.
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