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10.1016/B978-0-12-407697-6.00004-0 http://scihub22266oqcxt.onion/10.1016/B978-0-12-407697-6.00004-0 C5593132!5593132!23445810     free     free     free       Int+Rev+Cell+Mol+Biol 2013 ; 303 (ä): 139-202 Nephropedia Template TP {{tp|p=23445810|t=2013. Cellular and Molecular Biology of Airway Mucins |pdf=|usr=}}{{23445810}} gab.com Text Cellular and Molecular Biology of Airway Mucins JO: Int Rev Cell Mol Biol http://www.kidney.de/pget.php?&tw=1&pmid=23445810 #FOAvip Airway mucus constitutes a thin layer of airway surface liquid with component macromolecules that covers the luminal surface of the respiratory tract. The major function of mucus is to protect the lungs through mucociliary clearance of inhaled foreign particles and noxious chemicals. Mucus is comprised of water, ions, mucin glycoproteins, and a variety of other macromolecules, some of which possess anti-microbial, anti-protease, and anti-oxidant activities. Mucins comprise the major protein component of mucus and exist as secreted and cell-associated glycoproteins. Secreted, gel-forming mucins are mainly responsible for the viscoelastic property of mucus, which is crucial for effective mucociliary clearance. Cell-associated mucins shield the epithelial surface from pathogens through their extracellular domains and regulate intracellular signaling through their cytoplasmic regions. However, neither the exact structures of mucin glycoproteins, nor the manner through which their expression is regulated, are completely understood. This chapter reviews what is currently known about the cellular and molecular properties of airway mucins. Twit Text FOAVip Cellular and Molecular Biology of Airway Mucins ????Int Rev Cell Mol Biol http://www.kidney.de/pget.php?&tw=1&pmid=23445810 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=23445810 #FOAvip English Wikipedia <ref>{{Cite pmid|23445810}}</ref> Cellular and Molecular Biology of Airway Mucins #MMPMID23445810 Lillehoj EP; Kato K; Lu W; Kim KC Int Rev Cell Mol Biol 2013[]; 303 (ä): 139-202 PMID23445810show ga Airway mucus constitutes a thin layer of airway surface liquid with component macromolecules that covers the luminal surface of the respiratory tract. The major function of mucus is to protect the lungs through mucociliary clearance of inhaled foreign particles and noxious chemicals. Mucus is comprised of water, ions, mucin glycoproteins, and a variety of other macromolecules, some of which possess anti-microbial, anti-protease, and anti-oxidant activities. Mucins comprise the major protein component of mucus and exist as secreted and cell-associated glycoproteins. Secreted, gel-forming mucins are mainly responsible for the viscoelastic property of mucus, which is crucial for effective mucociliary clearance. Cell-associated mucins shield the epithelial surface from pathogens through their extracellular domains and regulate intracellular signaling through their cytoplasmic regions. However, neither the exact structures of mucin glycoproteins, nor the manner through which their expression is regulated, are completely understood. This chapter reviews what is currently known about the cellular and molecular properties of airway mucins. äCellular and Molecular Biology of Airway Mucins (epmc).pdf DeepDyve Pubget Overpricing