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10.1021/acschembio.5b00439 http://scihub22266oqcxt.onion/10.1021/acschembio.5b00439 C5592732!5592732 !26502318     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\26502318 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       ACS+Chem+Biol 2016 ; 11 (1 ): 25-30 Nephropedia Template TP {{tp|p=26502318 |t=2016. Wall teichoic acids prevent antibody binding to epitopes within the cell wall of Staphylococcus aureus |pdf=|usr=}}{{26502318 }} gab.com Text Wall teichoic acids prevent antibody binding to epitopes within the cell wall of Staphylococcus aureus JO: ACS Chem Biol http://www.kidney.de/pget.php?&tw=1&pmid=26502318 #FOAvip Staphylococcus aureus is a Gram-positive bacterial pathogen that produces a range of infections including cellulitis, pneumonia, and septicemia. The principle mechanism in antistaphylococcal host defense is opsonization with antibodies and complement proteins, followed by phagocytic clearance. Here we use a previously developed technique for installing chemical epitopes in the peptidoglycan cell wall to show that surface glycopolymers known as wall teichoic acids conceal cell wall epitopes, preventing their recognition and opsonization by antibodies. Thus, our results reveal a previously unrecognized immunoevasive role for wall teichoic acids in S. aureus: repulsion of peptidoglycan-targeted antibodies. Twit Text FOAVip Wall teichoic acids prevent antibody binding to epitopes within the cell wall of Staphylococcus aureus ????ACS Chem Biol http://www.kidney.de/pget.php?&tw=1&pmid=26502318 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=26502318 #FOAvip English Wikipedia <ref>{{Cite pmid|26502318 }}</ref> Wall teichoic acids prevent antibody binding to epitopes within the cell wall of Staphylococcus aureus #MMPMID26502318 Gautam S ; Kim T ; Lester E ; Deep D ; Spiegel DA ACS Chem Biol 2016[Jan]; 11 (1 ): 25-30 PMID26502318 show ga Staphylococcus aureus is a Gram-positive bacterial pathogen that produces a range of infections including cellulitis, pneumonia, and septicemia. The principle mechanism in antistaphylococcal host defense is opsonization with antibodies and complement proteins, followed by phagocytic clearance. Here we use a previously developed technique for installing chemical epitopes in the peptidoglycan cell wall to show that surface glycopolymers known as wall teichoic acids conceal cell wall epitopes, preventing their recognition and opsonization by antibodies. Thus, our results reveal a previously unrecognized immunoevasive role for wall teichoic acids in S. aureus: repulsion of peptidoglycan-targeted antibodies. |Antibodies/*metabolism [MESH] |Cell Wall/*metabolism [MESH] |Epitopes/chemistry/*metabolism [MESH] |Models, Biological [MESH] |Protein Binding/drug effects [MESH] |Staphylococcus aureus/*metabolism [MESH]Wall teichoic acids prevent antibody binding to epitopes within the ce(epmc).pdf DeepDyve Pubget Overpricing