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10.3389/fmicb.2017.01719 http://scihub22266oqcxt.onion/10.3389/fmicb.2017.01719 C5591951!5591951!28928730     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=28928730&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Front+Microbiol 2017 ; 8 (ä): ä Nephropedia Template TP {{tp|p=28928730|t=2017. FPR2: A Novel Promising Target for the Treatment of Influenza |pdf=|usr=}}{{28928730}} gab.com Text FPR2: A Novel Promising Target for the Treatment of Influenza JO: Front Microbiol http://www.kidney.de/pget.php?&tw=1&pmid=28928730 #FOAvip The Formyl-peptide receptor-2 (FPR2) is a seven transmembrane G protein-coupled receptor, which plays an important role in sensing of bacteria and modulation of immune responses. FPR2 is also used by viruses for their own profit. Annexin A1, one of the multiple ligands of FPR2, is incorporated in the budding virus membrane of influenza A viruses (IAV). Thereby, once IAV infect a host cell, FPR2 is activated. FPR2-signaling leads to an increase in viral replication, a dysregulation of the host immune response and a severe disease. Conversely, experiments using FPR2 antagonists in a preclinical model of IAV infections in mice showed that blocking FPR2 protects animals from lethal infections. Thus, FPR2 represents a very attractive host target against influenza. In this review we will give an overview on the pathogenesis of influenza with a focus on the role of FPR2 and we will discuss the advantages of using FPR2 antagonists to treat the flu. Twit Text FOAVip FPR2: A Novel Promising Target for the Treatment of Influenza ????Front Microbiol http://www.kidney.de/pget.php?&tw=1&pmid=28928730 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28928730 #FOAvip English Wikipedia <ref>{{Cite pmid|28928730}}</ref> FPR2: A Novel Promising Target for the Treatment of Influenza #MMPMID28928730 Alessi MC; Cenac N; Si-Tahar M; Riteau B Front Microbiol 2017[]; 8 (ä): ä PMID28928730show ga The Formyl-peptide receptor-2 (FPR2) is a seven transmembrane G protein-coupled receptor, which plays an important role in sensing of bacteria and modulation of immune responses. FPR2 is also used by viruses for their own profit. Annexin A1, one of the multiple ligands of FPR2, is incorporated in the budding virus membrane of influenza A viruses (IAV). Thereby, once IAV infect a host cell, FPR2 is activated. FPR2-signaling leads to an increase in viral replication, a dysregulation of the host immune response and a severe disease. Conversely, experiments using FPR2 antagonists in a preclinical model of IAV infections in mice showed that blocking FPR2 protects animals from lethal infections. Thus, FPR2 represents a very attractive host target against influenza. In this review we will give an overview on the pathogenesis of influenza with a focus on the role of FPR2 and we will discuss the advantages of using FPR2 antagonists to treat the flu. äFPR2: A Novel Promising Target for the Treatment of Influenza (epmc).pdf DeepDyve Pubget Overpricing